Correction: Bioinformatics analysis of ferroptosis-related hub genes and immunoinfiltration in myocardial ischemia/reperfusion following heart transplantation - Report - MDSpire
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Correction: Analysis of Key Ferroptosis-Related Genes and Immune Cell Infiltration in Myocardial Ischemia/Reperfusion Post-Heart Transplantation

  • By

  • Yuxi Zhang

  • Qiao Tang

  • Jiahui Cui

  • Yanan Li

  • Heng Xu

  • Zhen Qiu

  • Shaoqing Lei

  • Rui Xue

  • Qian Sun

  • Zhongyuan Xia

  • September 21, 2026

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Correction: Analysis of Key Ferroptosis-Related Genes and Immune Cell Infiltration

Background

Ferroptosis, a form of regulated cell death associated with iron metabolism, has been implicated in myocardial ischemia-reperfusion injury, which is a significant concern in heart transplantation. Understanding the role of ferroptosis in this context may provide insights into the mechanisms underlying graft dysfunction.

Data Highlights

No numerical or trial data is presented in the correction article.

Key Findings

  • Correction of Figure panel 7F was necessary for accurate representation of data.
  • Ferroptosis is linked to microvascular dysfunction during ischemia-reperfusion.
  • Iron-mediated phospholipid peroxidation is a contributing factor to myocardial injury.
  • Research continues to explore the relationship between ferroptosis and immune cell infiltration in cardiac contexts.

Clinical Implications

Clinicians should remain aware of the evolving understanding of ferroptosis in the context of myocardial ischemia-reperfusion injury.

Conclusion

The correction of the figure in this study is vital for the accuracy of research findings related to ferroptosis and its implications in heart transplantation.

Related Resources & Content

  1. BMC Cardiovascular Disorders, 2024 -- Correction: Analysis of Key Ferroptosis-Related Genes and Immune Cell Infiltration
  2. Frontiers in Cardiovascular Medicine — Iron-dependent ferroptosis in cardiac microvascular endothelial cells: a key link between dysregulated iron homeostasis and microcirculatory injury during myocardial ischemia-reperfusion
  3. Frontiers in Cardiovascular Medicine — Transcriptomic signatures and immune microenvironment of acute rejection after heart transplantation: an integrated bioinformatics analysis
  4. Basic Research in Cardiology — Raf Kinase Inhibitor Protein's Role in Myocardial Fibrosis During Increased Oxidative Stress Conditions
  5. Basic Research in Cardiology — Temporal Changes in Fibroblast Polarization During Myocardial Infarction Transition from Inflammatory to Angiogenic Functions
  6. Summary of the International Society for Heart and Lung Transplantation (ISHLT) Consensus Conference on Graft Dysfunction within the First 72 hours after Heart Transplantation_ A 10-year Update
  7. Summary of the International Society for Heart and Lung Transplantation (ISHLT) Consensus Conference on Graft Dysfunction within the First 72 hours after Heart Transplantation: A 10-year Update - ScienceDirect
  8. Heart transplantation in adults: Graft dysfunction - UpToDate
  9. Risk factors for primary graft dysfunction after heart transplantation—a systematic review and meta-analysis - ScienceDirect
  10. Risk factors for primary graft dysfunction after heart transplantation-a systematic review and meta-analysis - PubMed
  11. Machine perfusion across different donor pathways in heart transplantation: A systematic review and network meta-analysis.
  12. Outcomes After Donation After Circulatory Determination of Death Cardiac Transplantation: An International, Multicenter Retrospective Study | JACC: Heart Failure
  13. Ferroptosis in cardiovascular disease: regulatory mechanisms and therapeutic implications - PubMed
  14. The interaction between ferroptosis and myocardial ischemia–reperfusion injury: molecular mechanisms and potential therapeutic targets | European Journal of Medical Research | Springer Nature Link
  15. https://www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2025.1558484/pdf?utm_source=openai
  16. Bioinformatics analysis of ferroptosis-related hub genes and immunoinfiltration in myocardial ischemia/reperfusion following heart transplantation - PubMed

Original Source(s)

Correction: Bioinformatics analysis of ferroptosis-related hub genes and immunoinfiltration in myocardial ischemia/reperfusion following heart transplantation

  • by Yuxi Zhang, Qiao Tang, Jiahui Cui, Yanan Li, Heng Xu, Zhen Qiu, Shaoqing Lei, Rui Xue, Qian Sun, Zhongyuan Xia

  • September 21, 2026

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