Femoral neck system vs. cannulated screws for Pauwels type III femoral neck fracture in non-elderly patients: a systematic review and meta-analysis - Report - MDSpire

Femoral neck system vs. cannulated screws for Pauwels type III femoral neck fracture in non-elderly patients: a systematic review and meta-analysis

  • By

  • Junlong Song

  • Chan Kang

  • Jeong-Kil Lee

  • Rongcan Liu

  • Huan Chen

  • Junsheng Zhang

  • Sangheok Lee

  • Long Zheng

  • Jung-Mo Hwang

  • March 31, 2026

  • 0 min

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Comparison of Femoral Neck System and Cannulated Screws for Pauwels III Fractures

Overview

This meta-analysis of 10 studies including 557 non-elderly adults with Pauwels type III femoral neck fractures found that the femoral neck system (FNS) offers faster fracture healing, earlier weight-bearing, fewer complications, and better hip function compared to cannulated screws (CS). However, FNS was associated with increased intraoperative blood loss.

Background

Pauwels type III femoral neck fractures are unstable fractures common in non-elderly adults and are associated with high rates of complications such as nonunion and femoral head necrosis. Internal fixation is the primary treatment to preserve the native hip joint, with cannulated screws (CS) being widely used due to minimal trauma and surgical time. However, CS have limited shear resistance leading to fixation failure in these unstable fractures. The femoral neck system (FNS) is a newer fixation device designed to improve angular and rotational stability, potentially reducing complications and improving outcomes.

Data Highlights

OutcomeMeasureEffect Size (95% CI)P-value
Fracture Healing TimeStandard Mean Difference (SMD)−0.90 (−1.30, −0.49)<0.0001
Weight-Bearing TimeSMD−1.17 (−1.61, −0.74)<0.00001
Total ComplicationsOdds Ratio (OR)0.16 (0.08, 0.33)<0.00001
Harris Hip Score (HHS)Mean Difference (MD)2.07 (1.16, 2.97)<0.00001
Intraoperative Blood LossMD21.88 (12.48, 31.29)<0.00001

Key Findings

  • FNS significantly reduced fracture healing time compared to CS (SMD = −0.90; P < 0.0001).
  • Patients treated with FNS achieved earlier weight-bearing (SMD = −1.17; P < 0.00001).
  • FNS was associated with a markedly lower rate of total postoperative complications (OR = 0.16; P < 0.00001).
  • Hip function measured by Harris Hip Score was superior in the FNS group (MD = 2.07; P < 0.00001).
  • Intraoperative blood loss was greater in the FNS group by approximately 22 mL (MD = 21.88; P < 0.00001).

Clinical Implications

For non-elderly adults with Pauwels type III femoral neck fractures, FNS provides enhanced mechanical stability leading to faster healing and improved functional outcomes compared to traditional cannulated screws. Despite the trade-off of increased intraoperative blood loss, the reduced complication rates and earlier mobilization suggest FNS may be the preferred fixation method in this patient population.

Conclusion

The femoral neck system demonstrates superior clinical efficacy and safety over cannulated screws in treating unstable Pauwels type III femoral neck fractures in younger adults. These findings support the adoption of FNS as a more effective fixation strategy in this challenging fracture type.

References

  1. Systematic Review Registration PROSPERO CRD420251111561

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