Long-term Neurodevelopmental Assessments in Adolescents Born Very and Extremely Preterm
Overview
This study evaluates neurodevelopmental outcomes in adolescents born very or extremely preterm. Findings indicate significant correlations between early cognitive scores and later intellectual functioning, while psychiatric diagnoses were prevalent in this population.
Background
Preterm birth is a significant global health issue, with a high incidence of cognitive, motor, and emotional difficulties in survivors. This study aims to fill the gap in knowledge regarding the outcomes of preterm adolescents, particularly in Southern European populations.
Data Highlights
Age
MDI Score Correlation
PDI Score Correlation
3 months
ρ = 0.410 (p = 0.052)
N/A
12 months
ρ = 0.705 (p < 0.01)
N/A
18 months
ρ = 0.763 (p < 0.01)
ρ = 0.583 (p = 0.022)
Key Findings
50% of extremely preterm adolescents had psychiatric or neurodevelopmental diagnoses.
33.3% of very preterm adolescents were similarly diagnosed.
Visuomotor coordination negatively correlated with gestational age (r = –0.57).
MDI scores at 12 and 18 months were significantly predictive of later cognitive functioning.
Early motor scores showed inconsistent predictive associations, with only the 18-month PDI reaching significance.
Clinical Implications
The findings highlight the prevalence of psychiatric and neurodevelopmental diagnoses in adolescents born very or extremely preterm.
Conclusion
The study emphasizes the importance of early developmental assessments in predicting neurodevelopmental outcomes in preterm adolescents.
