Integration of Surface-Guided Radiation Therapy with Real-Time Position Management

Overview

This report discusses the integration of surface-guided radiation therapy (SGRT) with real-time position management (RPM) for deep inspiratory breath-hold (DIBH) in treating left breast cancer. The combination aims to enhance treatment precision and reduce radiation exposure to critical cardiac structures.

Background

Breast cancer remains the most common malignancy among women, necessitating effective radiotherapy strategies to minimize radiation-induced organ damage, particularly to the heart and lungs. DIBH has emerged as a promising technique to mitigate these risks by displacing critical structures away from radiation fields. However, existing methods face challenges in ensuring accurate patient positioning and breath-hold consistency.

Data Highlights

No numerical data available in the source material.

Key Findings

• DIBH significantly reduces radiation-induced cardiotoxicity and pulmonary complications in left breast cancer patients.
• SGRT provides a non-ionizing solution for monitoring patient positioning with submillimeter precision.
• Challenges with existing systems (ABC and RPM) include reliance on single-dimensional tracking and potential inaccuracies in breath-hold status.
• Combining SGRT with RPM aims to improve treatment efficiency and reduce setup errors.
• Clinical guidelines recommend real-time monitoring systems to ensure reproducible displacement during DIBH.

Clinical Implications

Healthcare professionals should consider integrating SGRT with RPM for DIBH in left breast cancer radiotherapy to enhance treatment accuracy and minimize cardiac exposure. Continuous monitoring and verification of breath-hold fidelity are essential to optimize patient outcomes.

Conclusion

The integration of SGRT and RPM represents a significant advancement in the management of left breast cancer radiotherapy, aiming to improve precision and reduce the risk of radiation-induced complications.

References

1. respiTrack: Individualized Real-Time Prediction of Respiratory Tumor Motion Through Magnetic Tracking Techniques, 2020
2. Application of IMRT-Enhanced Radiosurgery for the Management of Multiple or Large Irregular Intracranial Lesions and Evaluation of Infrared Frameless Localization Techniques, Journal of Neuro-Oncology, 2009
3. Assessing the Precision of Contouring and Dosimetric Effects in Contemporary MRI-Guided Adaptive Radiation Therapy for Brain Metastases: A Retrospective Analysis, Journal of Neuro-Oncology, 2024
4. Postmastectomy Radiation Therapy: An ASTRO-ASCO-SSO Clinical Practice Guideline, The ASCO Post, 2025
5. Deep inspiration breath hold versus free breathing in postoperative radiotherapy strategy for patients with left-sided breast cancer treated with volumetric modulated arc therapy: A meta-analysis and systematic review, PMC
6. Surface-guided radiotherapy systems in locoregional deep inspiration breath hold radiotherapy for breast cancer: a multicenter study on the setup accuracy, Tampere University Research Portal
7. The ASCO Post — Prone Position during Radiation Therapy for Breast Cancer Is Associated with Reduced Irradiation to Lung and Heart
8. Postmastectomy Radiation Therapy: An ASTRO-ASCO-SSO Clinical Practice Guideline
9. Deep inspiration breath hold versus free breathing in postoperative radiotherapy strategy for patients with left-sided breast cancer treated with volumetric modulated arc therapy: A meta-analysis and systematic review - PMC
10. Surface-guided radiotherapy systems in locoregional deep inspiration breath hold radiotherapy for breast cancer: a multicenter study on the setup accuracy - Tampere University Research Portal