An evaluation of factors associated with hypertension in children and adolescents with obesity - Report - MDSpire

An evaluation of factors associated with hypertension in children and adolescents with obesity

  • By

  • Zhou, Kexin

  • Cai, Zili

  • Xiang, Shiting

  • Wei, Jianhui

  • Deng, Manxin

  • Peng, Yunlong

  • Liu, Zhiyu

  • Tan, Jie

  • Zhu, Guanghui

  • Gong, Zhuo

  • Li, Qi

  • Zhu, Lemei

  • Qiu, Jun

  • April 30, 2026

  • 0 min

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Clinical Report: Assessing Risk Factors for Hypertension in Obese Children

Overview

This study identifies key risk factors for hypertension in obese children, highlighting the prevalence of hypertension at 20.6%. Independent risk factors include neutrophils, NLR, platelet count, albumin, and triglycerides.

Background

Childhood obesity and hypertension are significant global health concerns, with obesity being a major risk factor for developing hypertension in children. Understanding the relationship between these conditions is crucial for early intervention and management strategies. Identifying specific risk factors can aid healthcare professionals in targeting preventive measures and improving health outcomes in this vulnerable population.

Data Highlights

ParameterValue
Detection rate of hypertension20.6%
Mean age of participants11.9 ± 2.0 years

Key Findings

  • Hypertension prevalence in obese children is 20.6%.
  • Neutrophils (NE) and the neutrophil-to-lymphocyte ratio (NLR) are independent risk factors for hypertension.
  • Platelet count (PLT), albumin (ALB), and triglycerides (TG) also correlate with increased hypertension risk.
  • Linear relationships exist between NE, NLR, ALB, TG and both systolic and diastolic blood pressure.
  • A nonlinear dose-response relationship is observed between PLT and systolic blood pressure.

Clinical Implications

Healthcare providers should monitor neutrophil levels, NLR, PLT, ALB, and TG in obese children to assess hypertension risk. Early identification of these risk factors can facilitate timely interventions to prevent hypertension and its associated complications.

Conclusion

The study underscores the importance of recognizing specific hematological and biochemical markers as risk factors for hypertension in obese children. This knowledge can enhance screening and management strategies in pediatric populations.

Related Resources & Content

  1. Pediatric Cardiology, 2026 -- Associations of Overweight and Obesity Indicators with Cardiometabolic Risk Profile in Children and Adolescents with Congenital Heart Disease
  2. Pediatric Cardiology, 2020 -- Geometric Alterations of the Left Ventricle in Severely Obese Adolescents: Frequency, Influencing Factors, and Clinical Consequences
  3. Pediatric Cardiology, 2026 -- Child Opportunity Index and Prevalence of Obesity and Hypertension in Adolescents with Congenital Heart Disease
  4. Pediatric Cardiology, 2022 -- Influence of Gender and Body Weight on Echocardiographic Measurements in Pediatric and Adolescent Populations
  5. Global Prevalence of Hypertension in Children and Adolescents Younger Than 19 Years: A Systematic Review and Meta-Analysis, PubMed
  6. Hypertension in children and adolescents: emerging global evidence and clinical implications, Hypertension Research
  7. Non-linear effect of physical activity intervention on blood pressure in children and adolescents: a systematic review and dose-response meta-analysis, BMC Public Health
  8. Global Prevalence of Hypertension in Children and Adolescents Younger Than 19 Years: A Systematic Review and Meta-Analysis - PubMed
  9. Hypertension in children and adolescents: emerging global evidence and clinical implications | Hypertension Research
  10. Non-linear effect of physical activity intervention on blood pressure in children and adolescents: a systematic review and dose-response meta-analysis | BMC Public Health | Full Text

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