Racial Differences in Secondary Treatment Pathways and Survival in Localized Prostate Cancer - Report - MDSpire
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Disparities in Secondary Treatment Approaches and Survival Rates for Localized Prostate Cancer Among Racial Groups

  • By

  • Jessica Acolin

  • Yibai Zhao

  • Sarah K. Holt

  • John L. Gore

  • Ting Martin Ma

  • Ruth Etzioni

  • Yaw A. Nyame

  • July 21, 2026

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Clinical Report: Disparities in Secondary Treatment Approaches and Survival Rates for Localized Prostate Cancer Among Racial Groups

Overview

This study investigates racial disparities in secondary treatment receipt and mortality among Black and White patients with localized prostate cancer.

Background

Racial disparities in prostate cancer outcomes are significant, with Black men facing higher diagnosis and mortality rates compared to White men. Factors contributing to these disparities include differences in treatment access and quality of care.

Data Highlights

The study utilized SEER-Medicare data to analyze treatment patterns and outcomes among non-Hispanic Black and White patients aged 66 years or older diagnosed with prostate cancer from 2004 to 2017.

Key Findings

  • Black men are 1.6 times more likely to be diagnosed and over 2 times more likely to die from prostate cancer compared to White men.
  • Under equitable treatment conditions, Black and White patients experience similar outcomes.
  • Black patients receive fewer definitive treatments and experience delays in treatment compared to White patients.
  • Black patients have less frequent PSA surveillance.
  • Timely salvage radiation therapy at biochemical recurrence is associated with better outcomes.
  • This study examines how secondary treatment receipt may contribute to racial disparities in mortality among prostate cancer patients.

Clinical Implications

The study highlights disparities in secondary treatment receipt among Black patients with prostate cancer.

Conclusion

The findings indicate significant racial disparities in secondary treatment receipt and mortality among prostate cancer patients.

Related Resources & Content

  1. Shulman et al, JAMA Network Open, 2024 -- Disparities in Treatment Outcomes Among Non-Hispanic Black Patients With Locally Advanced Rectal Cancer
  2. Rude et al, Cancer, 2021 -- Study Investigates Influence of Race on Receipt of Care for Prostate Cancer
  3. Springer, 2021 -- Survival Benefits of External Beam Radiotherapy in Asian Patients with Metastatic Prostate Cancer Compared to Other Racial and Ethnic Groups
  4. The ASCO Post — Racial Disparities in Treatment of Common Lung Cancer Persist Despite Gains
  5. NCCN Prostate Cancer Guidelines Version 2.2026
  6. No racial disparities in prostate cancer-specific mortality after biochemical recurrence following radical prostatectomy or radiation therapy
  7. Disparities in guideline-concordant treatment receipt for localized prostate cancer (PCa): A SEER-based analysis.
  8. The association of where patients with prostate cancer live and receive care on racial treatment inequities - PubMed

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