Clinical Report: Evaluating the Prognostic Significance of Neutrophil-to-Lymphocyte Ratio in Early Outcomes of Surgical Patients with Intracerebral Hemorrhage

Overview

This study investigates the prognostic value of the neutrophil-to-lymphocyte ratio (NLR) in predicting early outcomes in patients undergoing surgery for intracerebral hemorrhage (ICH).

Background

Intracerebral hemorrhage (ICH) is a critical neurological emergency with high morbidity and mortality rates. Identifying reliable early prognostic indicators is essential for optimizing patient management. The neutrophil-to-lymphocyte ratio (NLR) serves as a potential marker reflecting systemic inflammation and immune dysregulation in ICH patients.

Data Highlights

Key Findings

• The poor prognosis group had significantly higher NLR at all time points (p < 0.001).
• NLR-D3 showed the highest correlation with 30-day mRS (r = 0.847).
• The AUC for NLR-D3 predicting poor prognosis was 0.802 (95% CI: 0.682, 0.922).
• Patients with NLR-D3 > 8.6 had an 82.9% poor prognosis rate.
• High NLR-D3 was identified as an independent risk factor for poor postoperative prognosis (p < 0.001).

Clinical Implications

Monitoring NLR may provide insights into patient outcomes following surgery for ICH.

Conclusion

Elevated NLR in the early postoperative period is associated with adverse outcomes in surgically treated ICH patients.

Related Resources & Content

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