Dynamic consent framework for low-dose CT scan lung cancer screening: autonomy, privacy, ethical data management - Report - MDSpire

Dynamic consent framework for low-dose CT scan lung cancer screening: autonomy, privacy, ethical data management

  • By

  • Jui-Chu Lin

  • Wesley Wei-Wen Hsiao

  • Jen-Wei Hu

  • Chien-Te Fan

  • June 10, 2026

  • 0 min

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Clinical Report: A Blockchain-Enhanced Dynamic Consent Model for LDCT Lung Cancer Screening

Overview

This report outlines the development of a blockchain-based dynamic consent framework for Low-Dose Computed Tomography (LDCT) lung cancer screening in Taoyuan, Taiwan. The model aims to enhance participant autonomy, privacy, and ethical data handling while integrating artificial intelligence for improved screening outcomes.

Background

Lung cancer remains a leading cause of cancer mortality globally, with early detection being crucial for improving survival rates. Low-Dose Computed Tomography (LDCT) has shown promise in reducing mortality through early diagnosis, yet challenges such as false positives and data privacy hinder its widespread implementation. A blockchain-enhanced consent model could address these issues by allowing participants to manage their consent preferences securely and transparently.

Data Highlights

The proposed blockchain-based dynamic consent system is currently being piloted with 15,000 participants in the Taoyuan Expanded Lung Cancer Screening Program.

Key Findings

  • The dynamic consent platform allows real-time modification of consent preferences.
  • Blockchain hash registration enhances data traceability and security.
  • AI-assisted risk assessment improves compliance with Taiwan's Personal Data Protection Act.
  • The framework supports precision health initiatives by integrating biobank data.
  • Implementation of this model addresses ethical and governance challenges in lung cancer screening.

Clinical Implications

Healthcare providers can leverage this blockchain-based consent model to enhance patient engagement and trust in lung cancer screening programs. By ensuring data privacy and autonomy, clinicians can improve participation rates and the ethical handling of sensitive health information.

Conclusion

The integration of a blockchain-enabled dynamic consent system in LDCT lung cancer screening programs represents a significant advancement in addressing privacy and ethical concerns, ultimately supporting better health outcomes.

Related Resources & Content

  1. European Radiology, 2023 -- Commercial AI for CT lung cancer screening: product capabilities, coverage of nodule management tasks and supporting evidence
  2. European Radiology, 2023 -- Impact of Reduced CT Radiation Dose on AI-Based Assessment of Incidental Lung Nodules for Malignancy
  3. The ASCO Post, 2013 -- Evolving Issues in Low-dose CT Lung Cancer Screening
  4. European Radiology, 2023 -- The Role of Artificial Intelligence in Assessing Risk-Dominant Lung Nodules: Impact of CT Reconstruction Settings
  5. United States Preventive Services Taskforce, 2021 -- Final Recommendation Statement: Lung Cancer: Screening
  6. New England Journal of Medicine, 2011 -- Reduced Lung-Cancer Mortality with Low-Dose Computed Tomographic Screening
  7. PubMed, 2015 -- Performance of Lung-RADS in the National Lung Screening Trial: a retrospective assessment
  8. Final Recommendation Statement: Lung Cancer: Screening | United States Preventive Services Taskforce
  9. Reduced Lung-Cancer Mortality with Low-Dose Computed Tomographic Screening | New England Journal of Medicine
  10. Performance of Lung-RADS in the National Lung Screening Trial: a retrospective assessment - PubMed

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