Meta-analysis of the effects of exercise intervention on physical health in individuals undergoing compulsory isolation - Report - MDSpire

Meta-analysis of the effects of exercise intervention on physical health in individuals undergoing compulsory isolation

  • By

  • Zhiyao Zhang

  • Zhuo Zhou

  • Hongmei Sun

  • Qinglu Wang

  • Maolin Zhang

  • May 1, 2026

  • 0 min

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Clinical Report: Systematic Review of Exercise Interventions in Drug Rehabilitation

Overview

This systematic review demonstrates that exercise interventions significantly enhance physical health in individuals undergoing compulsory drug rehabilitation. Key improvements were noted in flexibility, balance, muscular strength, and sensorimotor coordination.

Background

Drug addiction poses a significant public health challenge, impacting both physical and mental health. Chronic substance use leads to severe physiological damage, necessitating effective rehabilitation strategies. Exercise has emerged as a potential adjunctive treatment to improve physical health outcomes in this population.

Data Highlights

Physical Health IndicatorMean Difference (MD)95% Confidence Interval (CI)P-value
Sit-and-reach test3.92(3.23, 4.62)<0.001
Single-leg standing with eyes closed7.03(6.05, 8.02)<0.001
Grip strength1.23(0.06, 2.39)0.04
Choice reaction time-0.03(-0.05, -0.01)0.002
Vital capacity86.81(-1.56, 175.17)0.05

Key Findings

  • Exercise interventions significantly improved physical fitness indicators in drug rehabilitation individuals.
  • Improvements were noted in flexibility, balance, muscular strength, and sensorimotor coordination.
  • Statistical significance was achieved for most physical health indicators, except for vital capacity.
  • Recommended exercise regimen includes at least 3 sessions per week for over 12 weeks.
  • Psychological and neurocognitive outcomes were not assessed in this review, indicating a gap for future research.

Clinical Implications

Healthcare professionals should consider integrating structured exercise programs into drug rehabilitation protocols to enhance physical health outcomes. A combination of aerobic and traditional fitness exercises is recommended to address the multifaceted health deficits associated with substance use disorders.

Conclusion

This review underscores the importance of exercise as a beneficial intervention in the rehabilitation of individuals with substance use disorders, highlighting the need for further research to include psychological outcomes.

References

  1. npj Digital Medicine, 2025 -- Systematic review of dynamically tailored eHealth interventions targeting physical activity and healthy diet in chronic disease
  2. Springer, 2017 -- Feasibility of Lifestyle Modifications in Colorectal Cancer Patients: A Systematic Review Highlighting Potential Short-Term Health Advantages
  3. Techniques in Coloproctology, 2023 -- A Comprehensive Review of the Effects of Post-Surgery Aerobic Exercise Training on Patients with Intra-Abdominal Cancers
  4. Frontiers in Psychiatry, 2026 -- Efficacy of Health Professional-Led Psychological Interventions for Adult Cannabis Use in Community Environments: A Systematic Review and Meta-Analysis
  5. ASAM/AAAP, 2024 -- Clinical practice guideline management SUD
  6. Frontiers in Psychology, 2024 -- Effect of physical exercise on the emotional and cognitive levels of patients with substance use disorder: a meta-analysis
  7. MDPI, 2024 -- Effect of Tai Chi Compared to Running on Drug Cravings, Attention Bias, and Physical Fitness in Men with Methamphetamine Use Disorder
  8. JAM_240419 1..56
  9. Effect of physical exercise on the emotional and cognitive levels of patients with substance use disorder: a meta-analysis
  10. Effect of Tai Chi Compared to Running on Drug Cravings, Attention Bias, and Physical Fitness in Men with Methamphetamine Use Disorder

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