Case Report: Reversible acquired Chiari-like state and upper cervical syringomyelia caused by a giant posterior tentorial tumor confined to the supratentorial compartment - Report - MDSpire

Case Report: Reversible acquired Chiari-like state and upper cervical syringomyelia caused by a giant posterior tentorial tumor confined to the supratentorial compartment

  • By

  • Pablo Albiña-Palmarola

  • Ali Khanafer

  • Gottlieb Maier

  • Ketevan Mikeladze

  • Philipp von Gottberg

  • Oliver Ganslandt

  • Hans Henkes

  • July 15, 2026

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Clinical Report: Reversible Acquired Chiari-like Malformation Induced by Tumor

Overview

This case study presents a 39-year-old woman with acquired Chiari-like malformation and upper cervical syringomyelia due to a large posterior tentorial tumor. Following surgical intervention, imaging showed reversal of the Chiari-like state and resolution of the syrinx.

Background

Acquired Chiari-like malformations are rare and often secondary to intracranial lesions, which can lead to significant neurological symptoms. Understanding the pathophysiology behind these conditions is crucial for appropriate management.

Data Highlights

No numerical data or trial data presented in the article.

Key Findings

  • A 39-year-old woman presented with progressive headache, papilledema, and left homonymous hemianopia.
  • Imaging revealed a giant posterior tentorial mass causing significant mass effect and tonsillar descent.
  • Postoperative imaging showed restoration of normal tonsillar morphology and complete resolution of the syrinx.
  • Visual recovery was noted following treatment of the underlying tumor.

Clinical Implications

Clinicians should consider comprehensive imaging before proceeding with surgical decompression in patients with similar presentations.

Conclusion

The findings from this case highlight the potential for reversibility in acquired Chiari-like malformations when the causative lesion is effectively treated. Further research may be needed to explore the broader implications of these findings.

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