Latent profile analysis of nurses’ knowledge, attitude and practice regarding excessive oxygen therapy and influencing factors - Report - MDSpire

Latent profile analysis of nurses’ knowledge, attitude and practice regarding excessive oxygen therapy and influencing factors

  • By

  • Lingjun Luo

  • Linfei Li

  • Jingwen Zhang

  • Na Li

  • Zhongxian Yang

  • Chunchun Liu

  • Xianjuan Gou

  • June 5, 2026

  • 0 min

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Clinical Report: Analysis of Nurses' Knowledge and Practices on Oxygen Therapy

Overview

This study categorizes Chinese nurses' knowledge, attitudes, and practices (KAP) regarding excessive oxygen therapy into three distinct profiles. Significant factors influencing these profiles include age, work experience, and participation in training.

Background

Oxygen therapy is essential for treating hypoxia, but excessive oxygen can lead to hyperoxia and associated complications. Understanding nurses' KAP is crucial for ensuring safe and effective oxygen therapy, as they are the primary providers of this treatment. Variability in KAP among nurses can impact patient outcomes, highlighting the need for targeted educational interventions.

Data Highlights

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Key Findings

  • Three latent profile types identified: Low Knowledge–Moderately Attitude–Moderate Practice, Moderate Knowledge–Moderately Attitude–Moderate Practice, and High Knowledge–Positive Attitude–High Practice.
  • Age, work experience, professional title, education level, hospital level, training participation, and department significantly influence nurses' KAP.
  • The effective response rate of the survey was 92.46% with 687 valid responses from 743 collected questionnaires.
  • Standardizing oxygen therapy practices is crucial to avoid hyperoxia and ensure patient safety.
  • Previous studies show significant variability in nurses' KAP across different regions and settings.

Clinical Implications

Nursing managers and educators should develop targeted training programs based on the identified KAP profiles to enhance nurses' competencies in oxygen therapy. Continuous education and support are essential to improve patient safety and outcomes related to oxygen therapy.

Conclusion

The study highlights the importance of understanding nurses' KAP regarding excessive oxygen therapy and the need for tailored educational interventions. Addressing the identified influencing factors can lead to improved practices and patient safety.

Related Resources & Content

  1. Critical Care (Springer), 2025 -- Temporal Aspects of Oxygen Saturation Levels and Their Impact on Clinical Outcomes in Critically Ill Patients: A Retrospective Analysis Across Multiple Databases
  2. Intensive Care Medicine, 2010 -- The Influence of FiO2 Levels on Clinician Reactions to Hyperoxia in Ventilated Patients in a Dutch Intensive Care Unit
  3. Intensive Care Medicine, 2019 -- Recent Developments in Oxygen Toxicity During Major Emergency Surgical Procedures
  4. Frontiers in Pediatrics, 2026 -- Classification and influencing factors of parent activation among parents of preterm infants at a NICU in China: a latent profile analysis
  5. Annals of Intensive Care, 2024 -- Oxygen therapy in acute hypoxemic respiratory failure: guidelines from the SRLF-SFMU consensus conference
  6. JACC, 2024 -- 2025 ACC/AHA/ACEP/NAEMSP/SCAI Guideline for the Management of Patients With Acute Coronary Syndromes
  7. New England Journal of Medicine, 2019 -- Conservative Oxygen Therapy during Mechanical Ventilation in the ICU
  8. Oxygen therapy guidelines and recommendations
  9. Clinical guidelines for oxygen therapy in acute care
  10. Conservative Oxygen Therapy during Mechanical Ventilation in the ICU | New England Journal of Medicine

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