Effectiveness of a culturally adapted psychoeducational intervention for family caregivers of children with hematologic malignancy: a randomized controlled trial - Report - MDSpire

Effectiveness of a culturally adapted psychoeducational intervention for family caregivers of children with hematologic malignancy: a randomized controlled trial

  • By

  • Zhiyu Ye

  • Yuanyuan Zhang

  • Lisha Dai

  • Wentian Li

  • Fang Wang

  • June 2, 2026

  • 0 min

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Efficacy of a Culturally Tailored Psychoeducational Program for Family Caregivers

Overview

This study evaluated a culturally adapted psychoeducational intervention for caregivers of pediatric patients with hematologic cancers. Results indicated significant reductions in depressive and post-traumatic stress symptoms among caregivers in the intervention group compared to controls, with effects maintained at follow-up.

Background

Hematologic malignancies are among the most common pediatric cancers, imposing significant psychological burdens on family caregivers. Caregivers often experience heightened levels of anxiety, depression, and distress, particularly during the early stages of their child's illness. Timely psychosocial support is essential to mitigate these effects and improve caregiver well-being.

Data Highlights

GroupDepressive Symptoms ReductionPTSD Symptoms ReductionCaregiver Burden Reduction
InterventionSignificantSignificantDelayed
ControlNo significant changeNo significant changeNo significant change

Key Findings

  • The intervention group experienced greater reductions in depressive symptoms compared to the control group.
  • Post-traumatic stress symptoms also significantly decreased in the intervention group.
  • Caregiver burden showed a delayed reduction, becoming evident at follow-up assessments.
  • Anxiety levels decreased over time in both groups, but without significant differences between them.
  • The culturally tailored approach was effective in addressing the specific needs of caregivers.

Clinical Implications

Healthcare providers should consider implementing culturally tailored psychoeducational programs for caregivers of pediatric patients with hematologic cancers. Such interventions can significantly reduce psychological distress and caregiver burden, enhancing overall family well-being during challenging treatment phases.

Conclusion

The study supports the effectiveness of culturally adapted psychoeducational interventions in reducing psychological distress among caregivers of pediatric hematology patients. Continued exploration and implementation of such programs are warranted to improve caregiver support.

Related Resources & Content

  1. Frontiers in Psychiatry, 2026 -- Family psychoeducation to support patients with psychotic illness: two-year outcomes from a pre–post longitudinal pilot study
  2. The ASCO Post, 2014 -- Ongoing Clinical Trials Actively Recruiting Patients With Ovarian or Cervical Cancers
  3. Bone Marrow Transplantation, 2024 -- The 50th Annual Conference of the European Society for Blood and Marrow Transplantation: Psychiatry and Psychology Group – Poster Presentations
  4. Journal of Neuro-Oncology, 2023 -- Enhancing Carer Readiness Through a Supportive Educational Program for Caregivers of High-Grade Glioma Patients: Findings from a Randomized Controlled Trial
  5. Standards of Psychosocial Care for Parents of Children with Cancer - PMC, 2023
  6. Effectiveness of digital health on psychological well-being in parents of children with cancer: a systematic review and meta-analysis of randomized controlled trials | BMC Cancer, 2025
  7. BMT-CARE App: A Randomized Controlled Trial of a Psychosocial Digital Application for Caregivers of Patients Undergoing Hematopoietic Stem-Cell Transplantation - PubMed, 2023
  8. Standards of Psychosocial Care for Parents of Children with Cancer - PMC
  9. Effectiveness of digital health on psychological well-being in parents of children with cancer: a systematic review and meta-analysis of randomized controlled trials | BMC Cancer | Full Text
  10. BMT-CARE App: A Randomized Controlled Trial of a Psychosocial Digital Application for Caregivers of Patients Undergoing Hematopoietic Stem-Cell Transplantation - PubMed

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