Evaluating the psychosocial effects of cancer on sleep quality and mental health in elderly populations - Report - MDSpire

Evaluating the psychosocial effects of cancer on sleep quality and mental health in elderly populations

  • By

  • Yusheng Liu

  • Zheng Chen

  • Nanxia Lin

  • Yu Liu

  • Xuefeng Jiang

  • October 6, 2025

  • 0 min

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Impact of Cancer on Sleep Quality and Mental Well-Being in Older Adults

Overview

This study investigates the complex relationships between cancer diagnosis, sleep disturbances, and mental health among older adults. Findings highlight that cancer survivors experience significant challenges with sleep quality and increased depressive symptoms, which are influenced by socio-demographic factors and social engagement.

Background

Cancer incidence and survivorship are increasing globally, with over 54 million survivors worldwide. Older adults with cancer face compounded challenges due to chronic illness, mental health issues such as depression, and sleep disturbances. These factors interact bidirectionally, where poor sleep exacerbates mental health symptoms and vice versa, impacting overall quality of life and disease management. Addressing these interconnected issues is critical for improving outcomes in this growing population.

Data Highlights

The study utilized data from the 2018 wave of the Mexican Health and Aging Study (MHAS), a nationally representative cohort of adults aged 50 and older. Advanced statistical methods were applied to assess mediation effects of depression and social engagement on the relationship between cancer diagnosis and sleep disturbances, accounting for socio-demographic variables.

Key Findings

  • Cancer survivors among older adults report higher prevalence of sleep disturbances compared to non-cancer peers.
  • Depressive symptoms significantly mediate the relationship between cancer diagnosis and poor sleep quality.
  • Social engagement serves as a protective factor, mitigating the negative impact of cancer on mental health and sleep.
  • Socio-economic status and educational level influence the severity of mental health and sleep issues in cancer survivors.
  • Sleep disturbances and depression create a cyclical effect that can impair cancer treatment adherence and recovery.

Clinical Implications

Clinicians should adopt a holistic approach when managing older cancer survivors, incorporating routine screening for sleep disturbances and depressive symptoms. Early interventions such as cognitive-behavioral therapy targeting both insomnia and depression may improve patient outcomes. Additionally, addressing social determinants of health and promoting social engagement can enhance mental well-being and sleep quality in this vulnerable population.

Conclusion

Cancer diagnosis in older adults is intricately linked with poorer sleep quality and increased depressive symptoms, influenced by social and demographic factors. Integrative care strategies that address mental health and sleep disturbances alongside cancer treatment are essential to improve quality of life and health outcomes.

References

  1. World Health Organization 2022 -- Global Cancer Statistics
  2. Mexican Health and Aging Study (MHAS) 2018 -- Data Source

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