Guiding Principles for Physician-Modified Endografts - Report - MDSpire

Guiding Principles for Physician-Modified Endografts

  • By

  • Emiel W. M. Huistra

  • Clark J. Zeebregts

  • Robert C. Lind

  • July 10, 2026

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Key Considerations for Physician-Modified Endografts in Aortic Repair

Overview

Physician-modified endografts (PMEGs) provide an alternative for patients who cannot use custom-made devices (CMDs) for complex endovascular aortic repair. This report outlines the implementation of PMEGs.

Background

The management of complex aortic conditions often requires tailored solutions, particularly when CMDs are not feasible due to time or availability constraints. PMEGs allow for customization of endografts, which is critical for urgent cases. However, the technical demands of PMEGs necessitate expertise and standardized practices to ensure patient safety and procedural success.

Data Highlights

No specific numerical data provided in the source material.

Key Findings

  • PMEGs should be performed in specialized aortic centers with sufficient procedural volume and expertise.
  • Distinct skills are required for PMEG that differ from those used for CMDs.
  • Correct fenestration positioning is crucial for successful outcomes.
  • Operator and institutional experience correlate with improved procedural efficiency and reduced complication rates.
  • Variability exists in PMEG practices, highlighting the need for standardized workflows.

Clinical Implications

Healthcare providers should ensure that PMEG procedures are conducted in high-volume centers with the necessary expertise. Training and proctoring are essential for operators to navigate the complexities of PMEGs effectively.

Conclusion

The success of PMEGs depends on specialized training, experience, and adherence to best practices.

Related Resources & Content

  1. European Society for Vascular Surgery (ESVS), ORBi, 2025 -- ESVS 2026 Clinical Practice Guidelines on the Management of Descending Thoracic and Thoraco-Abdominal Aortic Diseases
  2. Journal of Endovascular Therapy, 2025 -- Optimizing PMEG Technique: Enhancing Endovascular Repair With Pre-Manufactured Fenestrated Endografts
  3. BJS (British Journal of Surgery), 2025 -- Results of a Prospective Multicenter Trial on Endovascular Repair of the Aortic Arch Using a Standard Modular Inner Branched Stent-Graft: An IDEAL 2a Study
  4. Journal of Endovascular Therapy, 2026 -- Endovascular Conversion of a Failed Fenestrated Anaconda Endograft Using a Branched Custom-Made Device
  5. sentara — Abdominal Aortic Aneurysm: When Endovascular Repair Is the Right Option
  6. FDA Summary of Safety and Effectiveness Data
  7. PubMed - Physician-Modified Fenestrated Stent Grafts Planned Using Three-Dimensional Techniques for Complex Aortic Pathology: A Systematic Review and Meta-Analysis
  8. ORBi: European Society for Vascular Surgery (ESVS) 2026 Clinical Practice Guidelines on the Management of Descending Thoracic and Thoraco-Abdominal Aortic Diseases. - 2025

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