Psychological Depression and Its Association with Oocyte Yield and Embryo Outcomes in Infertile Women Undergoing In Vitro Fertilization-Embryo Transfer - Report - MDSpire

Psychological Depression and Its Association with Oocyte Yield and Embryo Outcomes in Infertile Women Undergoing In Vitro Fertilization-Embryo Transfer

  • By

  • Song, Xiaohuan

  • Yin, Yitao

  • Jia, Yuedi

  • Wang, Jieyu

  • Wang, Danni

  • April 30, 2026

  • 0 min

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Clinical Report: Psychological Depression and IVF Outcomes in Infertile Women

Overview

Revise to specify the statistical significance of the reduction in retrieved oocytes.

Background

Infertility treatment through assisted reproductive technology (ART) can be significantly affected by psychological factors, particularly depression. Understanding the relationship between mental health and reproductive outcomes is crucial, as it may inform treatment protocols and support services for women undergoing IVF.

Data Highlights

OutcomeEffect Size (β)95% Confidence Interval
Transferable embryos-2.17-3.64 to -0.69
Retrieved oocytes-3.02-6.05 to -0.002

Key Findings

Incorporate p-values for the associations to provide a clearer understanding of significance.

Clinical Implications

Suggest specific screening tools or psychosocial interventions to be integrated into IVF protocols.

Conclusion

Depressive symptoms are significantly associated with reduced IVF-related reproductive outcomes, highlighting the importance of addressing mental health in infertility treatments.

Related Resources & Content

  1. BMC Psychiatry, 2025 -- Development and psychometric evaluation of a questionnaire addressing the psychosocial needs of oocyte recipient women
  2. The Journal of Clinical Endocrinology & Metabolism, 2025 -- Effects of Negative Pregnancy Experiences in the First IVF Cycle on Future Pregnancy Results
  3. Frontiers in Endocrinology, 2026 -- Editorial: Advancing reproductive outcomes: integrating molecular, metabolic, and endocrine insights into oocyte maturation
  4. Principles of care | Fertility problems: assessment and treatment | Guidance | NICE, 2026
  5. Frontiers | Psychological Depression and Its Association with Oocyte Yield and Embryo Outcomes in Infertile Women Undergoing In Vitro Fertilization-Embryo Transfer, 2026
  6. Frontiers in Endocrinology — Effect of basal LH levels on pregnancy outcome after IVF/ICSI fresh embryo transfer in patients of different ages: a retrospective study
  7. NICE Guidelines on Psychosocial Care in Fertility Treatment
  8. Frontiers | Psychological Depression and Its Association with Oocyte Yield and Embryo Outcomes in Infertile Women Undergoing In Vitro Fertilization-Embryo Transfer
  9. Patient distress and its negative impact on treatment continuation: do psychological interventions have a significant impact? | Human Reproduction | Oxford Academic

Original Source(s)

Psychological Depression and Its Association with Oocyte Yield and Embryo Outcomes in Infertile Women Undergoing In Vitro Fertilization-Embryo Transfer

  • by Song, Xiaohuan , Yin, Yitao , Jia, Yuedi , Wang, Jieyu , Wang, Danni

  • April 30, 2026

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