The Effect of Ultrasound-Guided Multipoint Thoracic Paravertebral Nerve Block in Metabolic and Bariatric Surgery (MBS): A Prospective Randomized Controlled Trial - Report - MDSpire

The Effect of Ultrasound-Guided Multipoint Thoracic Paravertebral Nerve Block in Metabolic and Bariatric Surgery (MBS): A Prospective Randomized Controlled Trial

  • By

  • Lijuan Li

  • Jing Wang

  • Tao Hu

  • Junmei Xu

  • Jiapeng Huang

  • August 18, 2025

  • 0 min

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Ultrasound-Guided Multipoint Thoracic Paravertebral Block Improves Outcomes in Bariatric Surgery

Overview

This randomized controlled trial demonstrated that ultrasound-guided multipoint thoracic paravertebral nerve block (TPVB) combined with general anesthesia significantly improved early recovery quality, reduced postoperative pain, and decreased opioid consumption in patients undergoing metabolic and bariatric surgery (MBS) compared to general anesthesia alone.

Background

Obesity prevalence is rapidly increasing globally, with metabolic and bariatric surgery (MBS) being an effective intervention for severe obesity and related metabolic disorders. Patients with obesity undergoing MBS are at increased risk of respiratory complications and heightened pain sensitivity. Opioids, commonly used for perioperative analgesia, pose risks including respiratory depression, especially in this population. Paravertebral nerve blocks have shown analgesic benefits in various surgeries but remain underexplored in MBS. This study investigates the efficacy and safety of ultrasound-guided multipoint TPVB in improving perioperative outcomes in MBS patients.

Data Highlights

OutcomeTPVB GroupGA GroupSignificance
Postoperative Pain LevelsSignificantly LowerHigherp < 0.05
Opioid ConsumptionReducedHigherp < 0.05
Early Recovery QualityImprovedLowerp < 0.05

Key Findings

  • Ultrasound-guided multipoint TPVB provides effective intraoperative and postoperative analgesia in MBS patients.
  • TPVB significantly reduces postoperative pain intensity compared to general anesthesia alone.
  • Patients receiving TPVB consume fewer opioids postoperatively, lowering opioid-related adverse effects.
  • Early recovery quality is enhanced in the TPVB group, suggesting better overall postoperative outcomes.
  • Ultrasound guidance enables precise localization of paravertebral space, critical in patients with obesity for safe and effective nerve block administration.

Clinical Implications

Incorporating ultrasound-guided multipoint TPVB into anesthesia protocols for MBS can optimize pain management while minimizing opioid use and associated respiratory risks in obese patients. This approach may enhance patient safety and recovery quality, addressing the unique challenges of analgesia in this high-risk population.

Conclusion

Ultrasound-guided multipoint thoracic paravertebral nerve block is a safe and effective adjunct to general anesthesia in metabolic and bariatric surgery, improving pain control, reducing opioid requirements, and enhancing early recovery. Its use should be considered to improve perioperative care in patients with obesity undergoing MBS.

References

  1. Global Obesity Trends and MBS Context, 2022
  2. Paravertebral Block Analgesic Benefits and Safety, 2024
  3. Clinical Trial Registration ChiCTR2400084190

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