Generating hepatitis B and D monitoring indicators in Germany using claims data: number of persons tested, incident and prevalent infections, 2016–2021 - Report - MDSpire

Generating hepatitis B and D monitoring indicators in Germany using claims data: number of persons tested, incident and prevalent infections, 2016–2021

  • By

  • Lisa Branke

  • Alexandra Hofmann

  • Anastassiya Stepanovich-Falke

  • Marco Alibone

  • Viviane Bremer

  • Ruth Zimmermann

  • Sandra Dudareva

  • June 2, 2026

  • 0 min

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Monitoring Indicators for Hepatitis B and D in Germany Derived from Claims Data

Overview

This study evaluates the use of claims data to monitor hepatitis B and D indicators in Germany from 2016 to 2021. It highlights the annual testing rates and prevalence of infections.

Background

Hepatitis B virus (HBV) infection is a significant global health issue, affecting over 250 million individuals. The World Health Organization (WHO) has set a goal to eliminate viral hepatitis as a public health threat by 2030, emphasizing the need for comprehensive monitoring systems. In Germany, existing data sources are limited, necessitating alternative methods like claims data to assess hepatitis prevalence and testing rates.

Data Highlights

No specific numerical data provided in the source material.

Key Findings

  • Claims data can provide insights into the annual number of persons tested for HBV and HDV.
  • Prevalent and newly detected HBV infections were assessed using claims data.
  • HDV infections among HBV-positive individuals were also evaluated.
  • The study discusses the plausibility of trends observed in claims data compared to national data sources.
  • Linkage to care could not be directly assessed due to limitations in claims data.

Clinical Implications

The findings suggest that claims data may serve as a valuable resource for monitoring hepatitis indicators, which is crucial for public health strategies. Enhanced data collection could improve understanding of hepatitis prevalence and inform healthcare responses.

Conclusion

The study demonstrates the potential of claims data to supplement existing hepatitis surveillance efforts in Germany, highlighting the need for improved data collection systems.

Related Resources & Content

  1. WHO, 2022 -- Guidelines for the prevention, diagnosis, care and treatment for people with chronic hepatitis B infection
  2. EASL, 2025 -- EASL Clinical Practice Guidelines on the management of hepatitis B virus infection
  3. RKI, 2025 -- Epidemiologisches Bulletin 14/2025
  4. ECDC, 2025 -- Testing of HIV, hepatitis B and hepatitis C in the European Union/European Economic Area
  5. Infection — Prevalence of Hepatitis D Virus Infection Among Individuals Coinfected with HIV and Hepatitis B Virus in Germany
  6. Infection — Analyzing HIV-Indicator Conditions in Two Nationwide Longitudinal Cohorts of Individuals Living with HIV in Germany (1999–2023)
  7. Infection — Implementation and Outcomes of a Comprehensive Screening Initiative for HIV, HBV, and HCV in an Emergency Department Setting
  8. Clinical Rheumatology — Identification of Significant Rates of Latent Tuberculosis and Positive Hepatitis B Serology in Rheumatology Patients Undergoing Enhanced Immunosuppressive Therapy in a Low-Incidence Region: The Importance of Screening
  9. EASL Clinical Practice Guidelines on the management of hepatitis B virus infection
  10. AASLD/IDSA Practice Guideline Update on Treatment of Chronic Hepatitis B
  11. Guidelines for the prevention, diagnosis, care and treatment for people with chronic hepatitis B infection
  12. Testing of HIV, hepatitis B and hepatitis C in the European Union/ European Economic Area (EU/EEA)
  13. RKI - Falldefinitionen
  14. Epidemiologisches Bulletin 14/2025
  15. Empfehlungen der Ständigen Impfkommission (STIKO) beim Robert Koch-Institut 2024
  16. EASL Clinical Practice Guidelines on hepatitis delta virus - Journal of Hepatology
  17. A Phase 3, Randomized Trial of Bulevirtide in Chronic Hepatitis D
  18. Bulevirtide Plus pegIFNα Superior to Bulevirtide Alone for Chronic HDV
  19. 1 Recommendations | Bulevirtide for treating chronic hepatitis D | Guidance | NICE
  20. 17 October 2024
  21. Clinical Testing and Diagnosis for Hepatitis B | Hepatitis B | CDC
  22. Hepatitis B, acute and chronic 2024 Case Definition | CDC

Original Source(s)

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