A systematic review utilizing registry data on lifestyle and non-drug oncology interventions across Africa - Report - MDSpire

A systematic review utilizing registry data on lifestyle and non-drug oncology interventions across Africa

  • By

  • Monica Wangari

  • Eunice Njoroge

  • Grace Mburu

  • Brenda Mogeni

  • Luke Ouma

  • April 1, 2026

  • 0 min

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Clinical Report: Systematic Review of Lifestyle Interventions in African Oncology

Overview

This systematic review identifies 53 clinical trials on lifestyle and non-drug interventions for cancer in Africa, revealing significant gaps in research and implementation. The majority of trials are concentrated in Egypt, with a focus on breast cancer and physical activity interventions.

Background

Cancer poses a major public health challenge in Africa, contributing to high morbidity and mortality rates. Lifestyle modifications have been shown to improve cancer outcomes, yet evidence from African settings is limited. Understanding the current landscape of lifestyle interventions is crucial for developing effective cancer management strategies in resource-limited environments.

Data Highlights

CountryNumber of Trials
Egypt38
Kenya4
Nigeria5

Key Findings

  • 53 trials on lifestyle and non-drug interventions for cancer were identified.
  • 71.7% of trials were conducted in Egypt, with significant underrepresentation in other African countries.
  • Breast cancer trials accounted for 45.3% of the total trials.
  • 47.2% of trials focused on physical activity interventions.
  • 84.9% of trials were sponsored by academic institutions.
  • 60.4% of the trials were completed, while 24.5% are ongoing.

Clinical Implications

Healthcare professionals should advocate for increased research and implementation of lifestyle interventions in cancer care across Africa. Integrating these interventions into oncology practice could enhance patient outcomes and quality of life.

Conclusion

The findings highlight the urgent need for more comprehensive research on non-pharmacological interventions in African oncology to address the unique challenges faced in these settings.

References

  1. Feasibility of Lifestyle Modifications in Colorectal Cancer Patients: A Systematic Review Highlighting Potential Short-Term Health Advantages, Springer, 2017
  2. Clinical Trials for Patients in Africa, The ASCO Post, 2013
  3. Lifestyle Changes Can Benefit Patients with Cancer, The ASCO Post, 2011
  4. American Cancer Society Guideline for Diet and Physical Activity for Cancer Survivors, American Cancer Society
  5. BMC Psychiatry (Springer) — A Systematic Review and Meta-Analysis of Suicidal Ideation and Actions in African Populations with Mental Health Disorders Over the Last 25 Years
  6. American Cancer Society Guideline for Diet and Physical Activity for Cancer Survivors | American Cancer Society
  7. Structured Exercise after Adjuvant Chemotherapy for Colon Cancer - PubMed
  8. Cancer registration status in Sub-Saharan Africa

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