Retraction: Integrative analysis of serum microorganisms and serum metabolomics in osteoporosis patients based on 16S rDNA sequencing and UHPLC/MS-based metabolomics - Report - MDSpire

Retraction: Integrative analysis of serum microorganisms and serum metabolomics in osteoporosis patients based on 16S rDNA sequencing and UHPLC/MS-based metabolomics

  • July 16, 2026

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Retraction Notice: Comprehensive Evaluation of Serum Microbiota and Metabolomic Profiles

Overview

The article detailing the integrative analysis of serum microorganisms and metabolomics in osteoporosis patients has been retracted due to concerns about data validity and lack of raw data. The retraction was approved by the Chief Editors of Frontiers in Medicine.

Background

Osteoporosis is a significant global health issue characterized by reduced bone density and increased fracture risk. Research in this area often explores novel biomarkers and metabolic profiles.

Data Highlights

No numerical data is available due to the retraction of the original study.

Key Findings

  • The original research article was retracted due to concerns about data validity.
  • The authors failed to provide raw data during the investigation.
  • The retraction was approved by the Chief Editors of Frontiers in Medicine.
  • The authors did not respond to correspondence regarding the retraction.

Clinical Implications

Healthcare professionals should be aware of the importance of data integrity in research publications.

Conclusion

The retraction of this article highlights the critical nature of data transparency and validity in scientific research.

Related Resources & Content

  1. Frontiers Editorial Office, Frontiers in Medicine, 2026 -- Retraction: Integrative analysis of serum microorganisms and serum metabolomics in osteoporosis patients based on 16S rDNA sequencing and UHPLC/MS-based metabolomics
  2. The Journal of Clinical Endocrinology & Metabolism — Correction to: "Efficient Short-duration, Low-impact, High-intensity Osteogenic Loading for Osteoporosis in Postmenopausal Women
  3. Frontiers in Immunology — The role of gut microbiota in osteoporosis: underlying mechanisms, clinical associations, and emerging biomaterials
  4. Frontiers in Endocrinology — Raman spectroscopic fingerprinting uncovers a multi-scale structural–mechanical–transcriptomic coupling landscape in osteoporosis
  5. The Journal of Clinical Endocrinology & Metabolism — Analysis of Circulating Micro-RNAs in Adults with Hypophosphatasia: Findings from the Initial Micro-RNA Study in HPP
  6. Final Recommendation Statement: Screening for Osteoporosis | United States Preventive Services Taskforce
  7. Pharmacologic Treatment of Primary Osteoporosis or Low Bone Mass to Prevent Fractures in Adults: A Living Clinical Guideline From the American College of Physicians (Version 1: Update Alert 1: Surveillance Note 1) - PMC
  8. Denosumab discontinuation in the clinic: implications of rebound bone turnover and emerging strategies to prevent bone loss and fractures - PubMed
  9. Risk of Cardiovascular Events in Patients with Osteoporosis on Romosozumab Treatment Compared with Denosumab: A Multicenter Observational Cohort Study - PubMed
  10. Clinical evidence linking osteoporosis and the gut microbiome in postmenopausal females: A systematic review - PubMed

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