Neurodevelopmental trajectories from birth to childhood and their impairments: insights from passive, spontaneous, and locomotor-like movements - Report - MDSpire

Neurodevelopmental trajectories from birth to childhood and their impairments: insights from passive, spontaneous, and locomotor-like movements

  • By

  • Damiana Rubeca

  • Francesca Sylos-Labini

  • Irina A. Solopova

  • Camilla Gizzi

  • Ambrogio Di Paolo

  • Arthur Dewolf

  • Yury Ivanenko

  • Francesco Lacquaniti

  • June 8, 2026

  • 0 min

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Clinical Report: Developmental Pathways of Motor Skills from Infancy to Early Childhood

Overview

This review highlights the progression of motor skills from prenatal stages through early childhood, emphasizing the importance of early detection of motor abnormalities in high-risk populations. It discusses the integration of observational tools and quantitative techniques to assess motor development and predict later impairments such as Cerebral Palsy.

Background

Expand on the link between early motor behaviors and specific neurodevelopmental disorders.

Data Highlights

No specific numerical data or trial results were provided in the source material.

Key Findings

  • Human motor behavior begins prenatally and evolves through various stages into childhood.
  • General Movements (GMs) serve as sensitive markers of neural integrity and are observable from pregnancy through early infancy.
  • The stepping reflex is an early expression of subcortical locomotor circuitry, indicating the precursor to voluntary walking.
  • Independent locomotion typically emerges between 10 and 15 months, influenced by musculoskeletal maturation and neural circuit refinement.
  • Quantitative kinematic and EMG techniques enhance the objective assessment of motor variability and coordination.
  • Early detection of deviations in motor behavior can predict later motor impairments, such as Cerebral Palsy.

Clinical Implications

Healthcare professionals should prioritize early surveillance and assessment of motor skills in infants, especially those at high risk for developmental disorders. Utilizing both observational and quantitative assessment tools can facilitate timely interventions that support optimal motor development.

Conclusion

The integration of various assessment methods is essential for the early identification of motor skill challenges in infants, which can lead to improved intervention strategies and outcomes. Continued research and clinical practice advancements are necessary to enhance early detection capabilities.

Related Resources & Content

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  5. CDC, Screening for Cerebral Palsy, 2026 -- Screening for Cerebral Palsy
  6. Effects of SAFE Early Intervention Approach in the First Months of Life in Infants at Risk, PMC, 2026 -- Effects of SAFE Early Intervention Approach
  7. CDC - Screening for Cerebral Palsy
  8. Effects of SAFE Early Intervention Approach in the First Months of Life in Infants at Risk: A Randomized Controlled Study - PMC

Original Source(s)

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