Clinical Report: Efficacy of 308-nm Excimer Laser in Treating FFA

Overview

{'text': 'This retrospective study evaluated the efficacy and safety of the 308-nm excimer laser in treating frontal fibrosing alopecia (FFA) in 30 patients. Results indicated stabilization or improvement in clinical symptoms for a majority of patients (specify percentage), suggesting the laser as a promising adjuvant treatment.'}

Background

Frontal fibrosing alopecia (FFA) is a progressive scarring alopecia that significantly impacts patients' quality of life. Current treatment options are limited, and many patients experience inadequate responses to existing therapies. The 308-nm excimer laser offers a potential new approach for managing this challenging condition.

Data Highlights

Key Findings

• 53.3% of patients experienced stabilization of the frontotemporal hairline.
• 20% showed improvement in clinical symptoms after 6 months of treatment.
• 83.3% had a one-grade improvement in erythema scores.
• 70% showed a one-grade improvement in perifollicular hyperkeratosis scores.
• Transient erythema was the only reported adverse effect, with 6.7% experiencing worsened erythema.

Clinical Implications

{'text': 'The 308-nm excimer laser may serve as an effective adjuvant treatment for patients with FFA who do not respond adequately to conventional therapies such as topical corticosteroids and JAK inhibitors. Clinicians should consider this option for symptomatic patients experiencing disease progression.'}

Conclusion

{'text': 'The findings support the use of the 308-nm excimer laser as a promising therapeutic option for FFA, highlighting its potential to improve clinical outcomes with a favorable safety profile. Further studies are needed to validate these findings and assess long-term effects.'}

Related Resources & Content

1. Frontiers in Medicine, 2026 -- Excimer 308-nm laser for the treatment of frontal fibrosing alopecia: an observational study in 30 patients
2. Consensus Document on the Clinical Management of Frontal Fibrosing Alopecia: Recommendations From Spanish Working Group on Trichology and Onychology of the AEDV - ScienceDirect
3. Randomized Controlled Trial of the Topical Jak Inhibitor Delgocitinib Cream in Patients with Frontal Fibrosing Alopecia - ScienceDirect
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8. Consensus Document on the Clinical Management of Frontal Fibrosing Alopecia: Recommendations From Spanish Working Group on Trichology and Onychology of the AEDV - ScienceDirect
9. Randomized Controlled Trial of the Topical Jak Inhibitor Delgocitinib Cream in Patients with Frontal Fibrosing Alopecia - ScienceDirect
10. Frontiers | Excimer 308-nm laser for the treatment of frontal fibrosing alopecia: an observational study in 30 patients