Global research trends and hotspots of short-chain fatty acids in cognitive impairment: a bibliometric analysis based on two databases - Report - MDSpire
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Global research trends and hotspots of short-chain fatty acids in cognitive impairment: a bibliometric analysis based on two databases
Clinical Report: Analyzing Global Research Patterns on SCFAs in Cognitive Impairment
Overview
This bibliometric study reviews literature on short-chain fatty acids (SCFAs) and cognitive impairment, identifying key contributors and emerging research trends. It highlights the increasing global interest in this area, particularly from China, and outlines the core themes of current research.
Background
Cognitive impairment is a significant public health challenge, affecting millions globally and linked to various adverse outcomes. Short-chain fatty acids (SCFAs), produced by gut microbiota, have been implicated in the regulation of cognitive functions.
Data Highlights
Database
Articles Retrieved
Web of Science Core Collection
425
Scopus
514
Key Findings
Annual publications on SCFAs and cognitive impairment have shown a continuous upward trend from 2009 to 2025.
China is the leading contributor to publications in this field, with Wenzhou Medical University identified as a core collaboration hub.
The International Journal of Molecular Sciences is a major publication platform for this research.
High-frequency keywords include “gut microbiota,” “Alzheimer’s disease,” and “neuroinflammation.”
Recent research frontiers focus on “drug therapy,” “microbiology,” and “chemistry.”
Clinical Implications
The findings indicate a growing body of literature linking SCFAs to cognitive impairment.
Conclusion
This bibliometric analysis clarifies the research landscape regarding SCFAs and cognitive impairment, highlighting the evolution of themes and potential future directions in this field.
