Variations in Carotid Bulb Geometry Among Asian and Caucasian Populations - Report - MDSpire

Variations in Carotid Bulb Geometry Among Asian and Caucasian Populations

  • By

  • Hossam Abdelmageed

  • Lamia Mbarek

  • Xuewei Xie

  • Yongjun Wang

  • Hui Li

  • Yang Liu

  • Huaguang Zheng

  • Robert Fleischmann

  • Jens P. Dreier

  • José Manuel Valdueza

  • April 21, 2026

  • 0 min

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Clinical Report: Variations in Carotid Bulb Geometry Among Asian and Caucasian Populations

Overview

Expand on how anatomical variations may specifically influence hemodynamics and plaque formation.

Background

Understanding carotid bifurcation geometry is crucial as it affects local hemodynamics and the development of atherosclerosis. Ethnic differences in carotid bulb morphology may contribute to varying patterns of carotid disease, with Asian populations exhibiting less extracranial atherosclerosis compared to Caucasians. This study aims to systematically characterize these differences.

Data Highlights

GroupCB/ICA Diameter Ratiop-value
Asian1.57<0.001
White1.68

Key Findings

  • Significant ethnic differences in carotid bulb geometry were observed.
  • The CB/ICA diameter ratio was lower in Asian participants compared to White participants (1.57 vs. 1.68; p < 0.001).
  • After adjustment for risk factors, the CB/ICA difference remained significant (−0.09; 95% CI -0.14 to −0.04; p < 0.001).
  • No significant interethnic difference in ICA diameter was found.
  • Carotid bulb diameter was smaller in Asian participants.

Clinical Implications

Detail specific ways clinicians can utilize this information in patient assessments.

Conclusion

The study underscores the importance of anatomical differences in carotid bifurcation geometry between ethnic groups, which may have significant implications for hemodynamics and atherosclerosis development.

References

  1. Gwon et al., Clinical Research in Cardiology, 2024 -- Identifying Stroke Risk Factors Associated with Surgical Intervention for Carotid Body Tumors
  2. Clinical Research in Cardiology, 2024 -- Nerve Distribution and Density in Proximity to the Carotid Artery Bifurcation
  3. Clinical Research in Cardiology, 2020 -- Collateral Arterial Anatomy as a Predictor of Intra-operative Somatosensory Evoked Potential Variations in Carotid Endarterectomy Patients
  4. PubMed, 2023 -- Systematic review of biomechanical forces associated with carotid plaque disruption and stroke
  5. USPSTF, 2024 -- Final Recommendation Statement: Asymptomatic Carotid Artery Stenosis: Screening
  6. Clinical Rheumatology — Enhancing Ultrasound Assessment of Carotid Artery Stenosis in Takayasu's Arteritis: Emphasizing Residual Inner Diameter as a Critical Metric
  7. Clinical context and consensus on carotid bifurcation geometry
  8. CREST-2: Stents But Not Endarterectomy Reduced Stroke Risk For Asymptomatic CAS
  9. Final Recommendation Statement: Asymptomatic Carotid Artery Stenosis: Screening | United States Preventive Services Taskforce

Original Source(s)

Variations in Carotid Bulb Geometry Among Asian and Caucasian Populations

  • by Hossam Abdelmageed, Lamia Mbarek, Xuewei Xie, Yongjun Wang, Hui Li, Yang Liu, Huaguang Zheng, Robert Fleischmann, Jens P. Dreier, José Manuel Valdueza

  • April 21, 2026

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