A Guideline-Concordant Chatbot Framework for Structured Colorectal Cancer Screening: Multistage Feasibility Study - Report - MDSpire

A Structured Chatbot Framework for Colorectal Cancer Screening Aligned with Guidelines: A Multistage Feasibility Assessment

  • By

  • Futao Wu

  • Xue Li

  • Yingyi Zeng

  • Yan Tang

  • Zhenhua Xiao

  • Siqi Yang

  • Kangcheng Wu

  • Side Liu

  • Aimin Li

  • July 16, 2026

Share

Clinical Report: A Structured Chatbot Framework for Colorectal Cancer Screening

Background

Colorectal cancer (CRC) is a significant global health concern, being the third most common cancer and a leading cause of cancer mortality. Screening is crucial for early detection and prevention, yet uptake remains low due to various barriers.

Data Highlights

No numerical data or trial data presented in the article.

Key Findings

  • Colorectal cancer screening is essential for reducing incidence and mortality.
  • Low awareness and psychological barriers contribute to suboptimal screening uptake.
  • Large language models (LLMs) are being integrated into healthcare for patient education.
  • Evidence supporting the use of LLMs in structured CRC screening workflows is limited.
  • Community adherence to CRC screening varies widely, from 13% to 55%.

Clinical Implications

Further research is needed to evaluate the effectiveness of chatbot frameworks in clinical settings.

Conclusion

Continued exploration of LLM applications in healthcare is warranted.

Related Resources & Content

  1. Sung H, Ferlay J, Siegel RL, et al., CA Cancer J Clin, 2021 -- Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries.
  2. US Preventive Services Task Force, JAMA, 2021 -- Screening for colorectal cancer: US Preventive Services Task Force recommendation statement.
  3. Zauber AG, Winawer SJ, O'Brien MJ, et al., N Engl J Med, 2012 -- Colonoscopic polypectomy and long-term prevention of colorectal-cancer deaths.
  4. Amlani B, Radaelli F, Bhandari P, PLoS One, 2020 -- A survey on colonoscopy shows poor understanding of its protective value and widespread misconceptions across Europe.
  5. Kew GS, Koh CJ, Gut Liver, 2020 -- Strategies to improve persistent adherence in colorectal cancer screening.
  6. DIGITAL HEALTH — Development of a cancer information chatbot model: Retrieval-augmented generation with data from the national center for cancer knowledge and information
  7. the asco post — ChatGPT Has Limitations in Clinical Utility for Colorectal Cancer but May Be Useful for Patient Education
  8. The ASCO Post — ASCO20 Virtual Scientific Program: Next-Generation Oncology Highlights
  9. npj Digital Medicine — Tailoring Prostate Cancer Education for Patients Through an EHR-Integrated Large Language Model Agent
  10. Final Recommendation Statement: Colorectal Cancer: Screening | United States Preventive Services Taskforce
  11. ChatGPT Has Limitations in Clinical Utility for Colorectal Cancer but May Be Useful for Patient Education
  12. Next-Generation Multitarget Stool DNA Test for Colorectal Cancer Screening
  13. Colonoscopies (screening)

Original Source(s)

Related Content