Clinical outcomes of plastic versus self-expanding metal stents in malignant hilar biliary obstruction - Report - MDSpire

Clinical outcomes of plastic versus self-expanding metal stents in malignant hilar biliary obstruction

  • By

  • Pastor Joaquín Ortiz Mendieta

  • Bruno da Costa Martins

  • Deborah Marques Centeno

  • Julia Mayumi Gregorio

  • Rafael Utimura Sueta

  • Adriana Vaz Safatle Ribeiro

  • Caterina Maria Pia Simoni Pennacchi

  • Carla Cristina Gusmon

  • Gustavo Andrade de Paulo

  • Luciano Henrique Lenz Tolentino

  • Marcelo Simas de Lima

  • Renata Nobre Moura

  • Sebastian Naschold Geiger

  • Fauze Maluf-Filho

  • July 8, 2026

  • 0 min

Share

Clinical Report: Comparative Analysis of Stents for Malignant Hilar Biliary Obstruction

Overview

This study evaluates the clinical success and stent patency rates of self-expanding metallic stents (SEMS) versus plastic stents (PS) in patients with unresectable malignant hilar biliary obstruction (MHBO).

Background

Malignant hilar biliary obstruction (MHBO) presents significant challenges in management due to its poor prognosis and high rates of recurrent biliary obstruction. Effective palliation is critical for maintaining quality of life and enabling ongoing treatment options such as chemotherapy.

Data Highlights

No numerical data was provided in the source material.

Key Findings

  • SEMS are associated with lower dysfunction rates compared to PS.
  • Some studies report improved clinical success and survival rates with SEMS, though results are not universally consistent.
  • Recurrent biliary obstruction can lead to complications such as acute cholangitis.
  • Patients with SEMS may experience a higher incidence of percutaneous transhepatic biliary drainage (PTBD).
  • Advances in systemic treatments may increase the need for interventions due to recurrent bile duct obstructions.

Clinical Implications

Clinicians should remain vigilant for complications such as recurrent biliary obstruction.

Conclusion

Further research is needed to solidify these findings.

Related Resources & Content

  1. Author(s)/Org, Source, Year -- Title
  2. Author(s)/Org, Source, Year -- Title
  3. Author(s)/Org, Source, Year -- Title
  4. Author(s)/Org, Source, Year -- Title
  5. ASGE guideline on the role of endoscopy in the management of malignant hilar obstruction
  6. Self-expandable metal stents versus plastic stents for unresectable malignant hilar biliary obstruction: A systematic review and meta-analysis of reconstructed individual patient data from randomized controlled trials with meta-regression - ScienceDirect
  7. ASGE guideline on the role of endoscopy in the management of malignant hilar obstruction
  8. Self-expandable metal stents versus plastic stents for unresectable malignant hilar biliary obstruction: A systematic review and meta-analysis of reconstructed individual patient data from randomized controlled trials with meta-regression - ScienceDirect

Original Source(s)

Clinical outcomes of plastic versus self-expanding metal stents in malignant hilar biliary obstruction

  • by Pastor Joaquín Ortiz Mendieta, Bruno da Costa Martins, Deborah Marques Centeno, Julia Mayumi Gregorio, Rafael Utimura Sueta, Adriana Vaz Safatle Ribeiro, Caterina Maria Pia Simoni Pennacchi, Carla Cristina Gusmon, Gustavo Andrade de Paulo, Luciano Henrique Lenz Tolentino, Marcelo Simas de Lima, Renata Nobre Moura, Sebastian Naschold Geiger, Fauze Maluf-Filho

  • July 8, 2026

Related Content

Higher Framingham steatosis index is associated with prevalent breast cancer in women: cross-sectional evidence from NHANES 1999–2018 and an exploratory hospital-based dataset

Bryan Johnson’s chronic disease is notoriously difficult to diagnose

Editorial: AI-driven smart sensing and processing for personalized healthcare