Invasive ventilation and association with outcomes in heart failure-related cardiogenic shock - Report - MDSpire

Invasive ventilation and association with outcomes in heart failure-related cardiogenic shock

  • By

  • Lisa Besch

  • Caroline Kellner

  • Jonas Sundermeyer

  • Benedikt N. Beer

  • Angela Dettling

  • Marvin Kriz

  • Carsten Skurk

  • Peter Lüdike

  • Tienush Rassaf

  • Stefan Kluge

  • Holger Thiele

  • Alastair Proudfoot

  • Tobias Graf

  • Enzo Lüsebrink

  • Paulus Kirchhof

  • Stefan Blankenberg

  • Benedikt Schrage

  • June 15, 2026

  • 0 min

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Impact of Invasive Ventilation on Outcomes in Patients with Cardiogenic Shock

Overview

This study evaluates the effects of invasive ventilation on clinical outcomes in patients with heart failure-related cardiogenic shock.

Background

Cardiogenic shock is a critical condition characterized by severe end-organ hypoperfusion due to low cardiac output, often requiring invasive ventilation.

Data Highlights

No numerical data provided in the source material.

Key Findings

  • Invasive ventilation is linked to higher mortality rates in patients with cardiogenic shock.
  • Patients requiring invasive ventilation had longer durations of ICU stay compared to those who did not.
  • Outcomes varied based on the severity of respiratory failure as indicated by the PaO2/FiO2 ratio.

Clinical Implications

Healthcare professionals should be aware of the potential negative outcomes associated with invasive ventilation in patients with cardiogenic shock. Careful consideration of the indications for intubation and ventilation strategies may be necessary to optimize patient outcomes.

Conclusion

Invasive ventilation significantly impacts outcomes in patients with heart failure-related cardiogenic shock, contributing to increased mortality and prolonged ICU stays. Further research is needed to explore optimal management strategies in this high-risk population.

Related Resources & Content

  1. Clinical Research in Cardiology, 2024 -- Exploring Ventilation Approaches in Cardiogenic Shock: Findings from the FRENSHOCK Observational Study
  2. Critical Care (Springer), 2025 -- Influence of different airway devices on intra-arrest ventilation during bag-valve-device ventilation - a prospective randomized controlled cadaver study
  3. Clinical Research in Cardiology, 2023 -- Impact of Combined VAV-ECMO, Impella CP, and Impella RP on Hemodynamics
  4. Clinical Research in Cardiology, 2010 -- The Use of Intracoronary Pyruvate as an Adjunct to Catecholamines and Intra-Aortic Balloon Pump in Cardiogenic Shock: Positive Impacts on Hemodynamics
  5. JACC, 2025 -- 2025 Concise Clinical Guidance: An ACC Expert Consensus Statement on the Evaluation and Management of Cardiogenic Shock
  6. JACC: Advances, 2025 -- Management Patterns and Outcomes of Invasive Mechanical Ventilation in Patients With Cardiogenic Shock
  7. European Journal of Heart Failure, 2023 -- Extracorporeal Membrane Oxygenation in the Therapy of Cardiogenic Shock: 1-Year Outcomes of the Multicentre, Randomized ECMO-CS Trial
  8. 2025 Concise Clinical Guidance: An ACC Expert Consensus Statement on the Evaluation and Management of Cardiogenic Shock: A Report of the American College of Cardiology Solution Set Oversight Committee | JACC
  9. Management Patterns and Outcomes of Invasive Mechanical Ventilation in Patients With Cardiogenic Shock | JACC: Advances
  10. Extracorporeal Membrane Oxygenation in the Therapy of Cardiogenic Shock: 1-Year Outcomes of the Multicentre, Randomized ECMO-CS Trial | European Journal of Heart Failure | Oxford Academic

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