Creation and assessment of a nomogram to forecast postoperative sleep issues in oral cancer patients: a prospective investigation - Report - MDSpire

Creation and assessment of a nomogram to forecast postoperative sleep issues in oral cancer patients: a prospective investigation

  • By

  • Ruyue Qiu

  • Yunyu Zhou

  • Guangman Wang

  • Jingya Yu

  • Yajun Li

  • Liyan Mao

  • Grace Paka Lubamba

  • Xiaoqin Bi

  • April 21, 2026

  • 0 min

Share

Clinical Report: Nomogram for Postoperative Sleep Issues in Oral Cancer Patients

Overview

This study developed and validated a nomogram to predict postoperative sleep disturbances in oral cancer patients. Key predictors included alcohol consumption, surgical duration, anxiety levels, and social support.

Background

Postoperative sleep disturbances (PSD) significantly affect recovery and quality of life in oral cancer patients. With a high incidence of sleep issues in this population, understanding risk factors is crucial for improving patient outcomes. Current literature lacks validated predictive models specifically for oral cancer, highlighting the need for targeted interventions.

Data Highlights

GroupIncidence of PSDAUCMAE
Training Set39.41%0.9020.0559
Validation Set39.66%0.9670.0942

Key Findings

  • 39.41% of patients in the training set experienced PSD.
  • Independent predictors of PSD included alcohol consumption, longer surgical duration, higher anxiety scores, and lower social support.
  • The nomogram demonstrated excellent discrimination with AUCs of 0.902 and 0.967 for training and validation sets, respectively.
  • Calibration curves indicated strong agreement between predicted and observed outcomes.
  • Decision curve analysis confirmed the model's clinical utility within a threshold probability range of 0.0-0.4.

Clinical Implications

Healthcare providers should consider the identified risk factors when assessing oral cancer patients for postoperative care. Implementing targeted interventions for those at higher risk may improve sleep quality and overall recovery.

Conclusion

The developed nomogram provides a valuable tool for predicting postoperative sleep disturbances in oral cancer patients, facilitating early identification and intervention strategies.

References

  1. Author(s)/Org, Source, Year -- Title
  2. BMC Psychiatry (Springer), 2025 -- Predicting sleep disturbance among patients with breast cancer in China through machine learning algorithms-a multi-site survey study
  3. Obesity Surgery, 2025 -- Structural and Functional Changes in the Upper Airway Following Laparoscopic Sleeve Gastrectomy: A Comprehensive Evaluation of Improvements in Obstructive Sleep Apnea
  4. AASM, 2023 -- New guideline establishes clinical recommendations for sleep apnea in hospitalized adults
  5. Obesity Surgery — Effects of Preoperative Dexamethasone on Recovery Quality After Laparoscopic Sleeve Gastrectomy: Findings from a Prospective Observational Study
  6. Sleep Quality in Head and Neck Cancer - PubMed
  7. Advances in the use of dexmedetomidine during the perioperative period to improve postoperative sleep quality
  8. New guideline establishes clinical recommendations for sleep apnea in hospitalized adults

Original Source(s)

Related Content