Author Correction: β-catenin confers resistance to PI3K and AKT inhibitors and subverts FOXO3a to promote metastasis in colon cancer - Report - MDSpire
Clinical Report: Correction to β-catenin and colon cancer metastasis report
Overview
A correction to the 2012 Nature Medicine report identifies a duplicated image in Fig. 6b under “T49, Xenograft.” The corrected panel replaces it with a different representative confocal image corresponding to the staining described in the article; the notice amends this specific error in the original publication.
Background
The original report, DOI 10.1038/nm.2772, was published online on 20 May 2012 and concerned β-catenin, resistance to PI3K and AKT inhibitors, and colon cancer metastasis. The correction addresses the accuracy of a figure panel rather than reporting new experimental findings. The supplied context does not provide additional methods, numerical results, or clinical outcomes from the original study.
Data Highlights
Item
Correction detail
Original report
Nature Medicine; DOI 10.1038/nm.2772; published online 20 May 2012
Location of error
Fig. 6b, “T49, Xenograft”
Identified issue
The panel contained an image duplicated from Fig. 1b
Correction
The corrected panel contains a different representative confocal image corresponding to the staining described
Key Findings
The correction concerns Fig. 6b of the report on β-catenin and colon cancer metastasis.
The “T49, Xenograft” image in the initially published Fig. 6b was duplicated from Fig. 1b.
The corrected Fig. 6b replaces that image with a different representative confocal image.
The notice states that the replacement image corresponds to the staining described in the article.
The correction amends the identified figure error; the supplied notice does not report other changes or new findings.
Clinical Implications
This notice documents a correction to a representative image and does not provide new clinical outcome data or treatment guidance. The supplied material does not establish implications for patient management.
Conclusion
The correction replaces the duplicated “T49, Xenograft” image in Fig. 6b with the intended representative confocal image. Its stated scope is limited to this figure-panel amendment.
by Stephan P. Tenbaum, Paloma Ordóñez-Morán, Isabel Puig, Irene Chicote, Oriol Arqués, Stefania Landolfi, Yolanda Fernández, José Raúl Herance, Juan D. Gispert, Leire Mendizabal, Susana Aguilar, Santiago Ramón y. Cajal, Simó Schwartz, Ana Vivancos, Eloy Espín, Santiago Rojas, José Baselga, Josep Tabernero, Alberto Muñoz, Héctor G. Palmer
