Clinical Report: Empowering Older Women to Alleviate Pain and Enhance Mood

Overview

The DAPPER and Women in PRIME studies highlight adaptations made to interventions targeting pain and depression in older women. Key changes led to improved retention and participation.

Background

Chronic pain and depression are prevalent among older women, often exacerbated by social determinants of health. Effective management of these comorbid conditions is important for improving quality of life in this population.

Data Highlights

No numerical data was provided in the source material.

Key Findings

• Seven adaptations were made from the DAPPER Study to the Women in PRIME Study.
• The intervention was renamed to Women in PRIME to reflect its broader focus.
• Retention practices were added to enhance participant engagement.
• The inclusion criteria expanded to encompass women of all races.
• Group Acceptance & Commitment Therapy (ACT) sessions were introduced.
• Individual nurse visits were reduced from 8 to 5 to streamline the intervention.

Clinical Implications

Engaging participants in the design process can enhance the relevance of health interventions.

Conclusion

The changes made from DAPPER to Women in PRIME resulted in greater retention and participation.

Related Resources & Content

1. Frontiers in Digital Health, 2026 -- A mobile intervention to reduce pain and improve health-III: protocol for a remotely delivered randomized controlled trial of physical activity for pain management in older adults with obesity and knee or hip osteoarthritis
2. The ASCO Post, 2017 -- Clinical Trials Actively Recruiting Geriatric Oncology Patients
3. The ASCO Post, 2015 -- Coping With Aging and Cancer: Psychosocial Factors and Geriatric-Specific Interventions
4. Frontiers in Pain Research, 2026 -- Longitudinal predictor analysis of pain in breast cancer survivors on aromatase inhibitors—the PAC-WOMAN trial
5. Recommendation: Depression and Suicide Risk in Adults: Screening | United States Preventive Services Taskforce
6. Effective Components of Collaborative Care for Depression in Primary Care: An Individual Participant Data Meta-Analysis - PubMed
7. A protocol for a wait list control trial of an intervention to improve pain and depressive symptoms among middle-age and older women living with disability - PMC
8. Recommendation: Depression and Suicide Risk in Adults: Screening | United States Preventive Services Taskforce
9. Effective Components of Collaborative Care for Depression in Primary Care: An Individual Participant Data Meta-Analysis - PubMed
10. A protocol for a wait list control trial of an intervention to improve pain and depressive symptoms among middle-age and older women living with disability - PMC