Correction to: Prediction of Symptoms and Evaluation of Surgical Indications After Birth Based on Tracheal Morphology of Double Aortic Arch - Report - MDSpire
Advertisement
Correction to: Prediction of Symptoms and Evaluation of Surgical Indications After Birth Based on Tracheal Morphology of Double Aortic Arch
Erratum: Corrections to Tracheal Diameter Predictions in Double Aortic Arch Study
Overview
This erratum addresses transcription and calculation errors in the original study on predicting tracheal diameter and assessing surgical criteria in double aortic arch cases. Corrections to the regression formula and Z-score calculations were made, but these did not affect the statistical significance or study conclusions.
Background
The original study focused on forecasting symptoms and evaluating surgical criteria postnatally based on fetal tracheal structure in patients with double aortic arch. Accurate prediction of normal tracheal diameter (NTD) and its Z-scores is critical for clinical decision-making. The study employed regression formulas and statistical analyses including ROC curves and intraclass correlation coefficients to validate findings.
Data Highlights
Parameter
Incorrect Value
Corrected Value
NTD Z scores (median symptomatic vs. asymptomatic)
−1.8 vs. −1.2 (P = 0.012)
−2.1 vs. −1.4 (P = 0.014)
NTD Z score threshold (ROC analysis)
≤ −1.7 (AUC 0.87, 95% CI: 0.69–1.00)
≤ −1.9 (AUC 0.85, 95% CI: 0.63–1.00)
Correlation coefficient (r) between variables
0.59 (95% CI: 0.23–0.81, P = 0.0037)
0.58 (95% CI: 0.21–0.81, P = 0.0046)
Intraclass correlation coefficient (NTD Z-score)
0.95 (95% CI: 0.81–0.99)
0.93 (95% CI: 0.75–0.98)
Interobserver agreement
0.87 (95% CI: 0.57–0.96)
0.87 (95% CI: 0.58–0.97)
Regression formula for predicted NTD [mm]
Predicted NTD = (−1.423 × GA) + 0.147
Predicted NTD = −1.423 + 0.147 × GA
Key Findings
The originally published regression formula description contained a transcription error but analyses used the correct formula.
Gestational age was initially entered as completed weeks only; corrected to include fractional weeks for Z-score calculations.
The predicted standard deviation calculation used √2 instead of the correct √(π/2), requiring recalculation of NTD Z-scores.
Corrected NTD Z-scores showed slightly lower median values in symptomatic versus asymptomatic groups (−2.1 vs. −1.4) compared to original values.
ROC curve analysis threshold for NTD Z-score changed from ≤ −1.7 to ≤ −1.9 with minimal impact on AUC and statistical significance.
Intraclass correlation coefficients and interobserver agreement remained high after corrections, supporting measurement reliability.
Clinical Implications
Clinicians should note the corrected regression formula and Z-score thresholds when assessing fetal tracheal diameter in double aortic arch cases. Despite recalculations, the predictive value of NTD Z-scores for symptom forecasting and surgical decision-making remains robust. Accurate gestational age input and formula application are essential for reliable assessments.
Conclusion
The erratum clarifies important methodological corrections without altering the original study’s conclusions. The validated predictive models for tracheal diameter and symptom assessment in double aortic arch remain clinically applicable.