Psychological distress experiences among patients living with HIV: a qualitative systematic review - Report - MDSpire

Psychological distress experiences among patients living with HIV: a qualitative systematic review

  • By

  • Xiao Xu

  • Zhenshuai Yao

  • Xiaofang Zhu

  • Jin Wang

  • Shuting Tan

  • Pingping He

  • June 12, 2026

  • 0 min

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Experiences of Psychological Distress in Individuals with HIV: A Qualitative Systematic Review

Overview

This systematic review consolidates evidence on psychological distress in HIV patients, highlighting individual, environmental, and interpersonal factors influencing their experiences.

Background

Psychological distress is a significant concern for individuals living with HIV, affecting their quality of life and overall health outcomes. Understanding the sources and factors contributing to this distress is essential for healthcare providers.

Data Highlights

A total of 1583 studies were identified, with 11 studies included in the review.

Key Findings

  • Three analytical themes emerged: individual factors, environmental factors, and interpersonal factors.
  • Individual factors include disease diagnosis and emotional dilemmas faced by patients.
  • Environmental factors encompass economic hardship, social environment, and limited access to health support.
  • Interpersonal factors involve decline in marital intimacy and insufficient support from family and friends.
  • Psychological distress is a subjective phenomenon influenced by multiple interacting factors.

Clinical Implications

Healthcare providers should prioritize understanding the psychological distress experienced by HIV patients to implement effective psychosocial care interventions. Tailored approaches that address the specific needs of individuals can enhance mental health and facilitate better integration into society.

Conclusion

The study presents the multifaceted nature of psychological distress in HIV patients.

Related Resources & Content

  1. BMC Psychiatry (Springer), 2025 -- Depressive disorders are associated with brain structural injury in HIV-positive men who have sex with men
  2. Open Forum Infectious Diseases -- Outcomes of HIV Care Continuum in Latin American and Caribbean Adolescents and Young Adults: Links to Depression and Substance Use
  3. Open Forum Infectious Diseases -- Elevated Levels of Depression and Anxiety in Men and Transgender Women Accessing Sexual Health Services in New York City During the COVID-19 Pandemic
  4. BMC Psychiatry (Springer) -- Assessment of the Viability and Acceptance of Systematic Depression Screening for Individuals with HIV in Senegal: Insights from a Qualitative Analysis of Diverse Stakeholders
  5. WHO guideline on HIV service delivery
  6. HIVMA/IDSA 2024 Primary Care Guidance Update for Providers Who Care for Persons with Human Immunodeficiency Virus
  7. Initiation of Antiretroviral Therapy | NIH
  8. Prevalence and associated factors of ICD/DSM-diagnosed depressive disorders among people living with HIV: A systematic review and meta-analysis - ScienceDirect
  9. Depressive symptoms and its determinants among people living with HIV in Africa: systematic review and meta-analysis | BMC Psychiatry | Springer Nature Link
  10. Global mental health disparities among transgender women and transfeminine people living with HIV: a systematic review and meta-analysis of 63 studies - ScienceDirect
  11. A Placebo-Controlled Randomized Trial of the Effects of Escitalopram on Depressive Symptoms and Immune Function in People With HIV - PubMed
  12. Integrated PTSD and Adherence Treatment for People with HIV: Main Findings of a Feasibility Pilot for Cognitive Processing Therapy-Lifesteps (CPT-L) - PubMed
  13. WHO guideline on HIV service delivery
  14. HIVMA/IDSA 2024 Primary Care Guidance Update for Providers Who Care for Persons with Human Immunodeficiency Virus
  15. Initiation of Antiretroviral Therapy | NIH
  16. Prevalence and associated factors of ICD/DSM-diagnosed depressive disorders among people living with HIV: A systematic review and meta-analysis - ScienceDirect
  17. Depressive symptoms and its determinants among people living with HIV in Africa: systematic review and meta-analysis | BMC Psychiatry | Springer Nature Link
  18. Global mental health disparities among transgender women and transfeminine people living with HIV: a systematic review and meta-analysis of 63 studies - ScienceDirect
  19. A Placebo-Controlled Randomized Trial of the Effects of Escitalopram on Depressive Symptoms and Immune Function in People With HIV - PubMed
  20. Integrated PTSD and Adherence Treatment for People with HIV: Main Findings of a Feasibility Pilot for Cognitive Processing Therapy-Lifesteps (CPT-L) - PubMed

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