Clinical Report: Diabetic Ketoacidosis and Reversible Sepsis-Induced Cardiomyopathy
Overview
This case study presents a 57-year-old female with poorly controlled type 2 diabetes who developed diabetic ketoacidosis (DKA) and sepsis-induced cardiomyopathy (SICM) due to a periapical abscess. Following management, including antibiotics and fluid resuscitation, the patient showed improvement in cardiac function.
Background
Diabetic ketoacidosis (DKA) is a critical complication of diabetes, often triggered by infections, with odontogenic infections being a significant source. The relationship between diabetes and sepsis can lead to severe outcomes, including multi-organ dysfunction and cardiomyopathy.
Data Highlights
Case presentation: A 57-year-old female with DKA (pH 7.04, -hydroxybutyrate 7.19 mmol/L) and sepsis (procalcitonin 2.34 ng/mL) showed severe left ventricular dysfunction (ejection fraction 36%). Follow-up echocardiography on day 14 demonstrated recovery (ejection fraction 72%).
Key Findings
Odontogenic infections can precipitate DKA and sepsis in diabetic patients.
The patient exhibited severe DKA and SICM.
Implementation of sepsis management protocols, including antibiotics and fluid resuscitation, was crucial for recovery.
Recovery of cardiac function was observed after addressing the underlying infection and metabolic derangements.
Physical examination, including oral cavity inspection, is vital in evaluating patients with DKA or sepsis.
Clinical Implications
Healthcare professionals should be aware of odontogenic infections in diabetic patients presenting with DKA.
Conclusion
This case illustrates the link between odontogenic infections and metabolic complications in diabetes.
