Burden of and risk factors for neurological complications in critical illness - Report - MDSpire

Burden of and risk factors for neurological complications in critical illness

  • By

  • Victoria A. McCredie

  • Thomas P. Bleck

  • Sherry Hsiang-Yi Chou

  • E. Wesley Ely

  • Margaret S. Herridge

  • Julie Kromm

  • Pedro Kurtz

  • Nicola Latronico

  • Mypinder S. Sekhon

  • Gentle Sunder Shrestha

  • Romain Sonneville

  • Robert D. Stevens

  • Shawniqua Williams Roberson

  • Tarek Sharshar

  • June 30, 2026

  • 0 min

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Clinical Report: Impact and Contributing Factors of Neurological Issues in Critically Ill Patients

Overview

Neurological complications in critically ill patients without primary brain injury are prevalent and linked to increased mortality and prolonged ICU stays. These complications arise from systemic and patient-related factors.

Background

Neurological complications are significant contributors to morbidity and mortality in ICU patients, often leading to long-term cognitive impairment and functional disability. Despite their impact, these complications remain underrecognized and inconsistently addressed in critical care.

Data Highlights

No numerical data provided in the source material.

Key Findings

  • Neurological complications are common in critically ill patients without primary brain injury.
  • These complications are associated with increased mortality and prolonged ICU stays.
  • Delirium, stroke, seizures, and neuromuscular disorders are frequently underrecognized manifestations of critical illness.
  • Systemic and treatment-related factors can precipitate acute brain injury even in the absence of a primary neurological insult.

Clinical Implications

Healthcare providers should be vigilant in recognizing neurological complications in critically ill patients and consider implementing standardized surveillance practices. Integrated neuroprotective strategies may help mitigate the long-term effects of these complications.

Conclusion

Neurological complications in critically ill patients represent a significant clinical challenge that requires improved recognition and management strategies to enhance patient outcomes.

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