Assessment of Sexual Dysfunction Rates and Associated Factors in Cancer Patients: A Systematic Review and Meta-Analysis - Report - MDSpire

Assessment of Sexual Dysfunction Rates and Associated Factors in Cancer Patients: A Systematic Review and Meta-Analysis

  • By

  • Amirmohammad Dahouri

  • Mina Hosseinzadeh

  • Mohammad Hasan Sahebihagh

  • January 28, 2026

  • 0 min

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Clinical Report: Assessment of Sexual Dysfunction Rates in Cancer Patients

Overview

This systematic review and meta-analysis reveals high rates of sexual dysfunction (SD) among cancer patients, with prevalence varying significantly by cancer type and treatment modality. The findings underscore the need for improved recognition and management of sexual health issues in oncology care.

Background

Cancer is a leading cause of death globally, and its impact extends beyond physical health to include significant effects on sexual health. Sexual dysfunction is prevalent among cancer patients, yet it remains underrecognized and inadequately addressed in clinical practice. Understanding the prevalence and determinants of SD is crucial for enhancing the quality of life for cancer survivors.

Data Highlights

No specific numerical data provided in the source material.

Key Findings

  • Sexual dysfunction affects 86-91% of patients with prostate, breast, and gynecological cancers.
  • Prevalence rates of sexual dysfunction range from 53-79% in head and neck, hematologic, and colorectal cancers.
  • Barriers to discussing sexual health include patient reluctance and healthcare providers' lack of training.
  • Only 2% of patients with advanced cancer were sexually active despite 62% desiring intimacy.
  • Existing literature on sexual dysfunction in cancer survivors is fragmented and inconsistent.

Clinical Implications

Healthcare providers should routinely assess sexual health in cancer patients to address the high prevalence of sexual dysfunction. Training and resources are needed to facilitate open discussions about sexual health and to implement effective management strategies.

Conclusion

Addressing sexual dysfunction is essential for holistic cancer care, and this study highlights the urgent need for systematic assessment and intervention in oncology settings.

References

  1. ASCO Post, 2021 -- Overcoming Gender Disparity in Evaluating Sexual Health Following a Cancer Diagnosis
  2. ASCO Post, 2013 -- Sexual Health after Cancer: Communicating with Your Patients Related Articles
  3. ASCO Post, 2020 -- Sexual Health Often Overlooked in Cancer Survivorship Care KEY POINTS
  4. ASCO Post, 2014 -- Discussing Sexual Health Issues With Female Cancer Survivors
  5. PubMed, 2026 -- The prevalence and risk factors of female sexual dysfunction in breast cancer survivors: a systematic review and meta-analysis
  6. Mayo Clinic -- Survivorship, Version 2.2025 Featured Updates to the NCCN Guidelines®
  7. JAMA Network -- Exercise and Psychosexual Education to Improve Sexual Function in Men With Prostate Cancer: A Randomized Clinical Trial
  8. The prevalence and risk factors of female sexual dysfunction in breast cancer survivors: a systematic review and meta-analysis - PubMed

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