Correction: Factors Influencing Pancreatic Dimensions and Adipose Tissue in UK Biobank

Overview

This correction addresses errors in the Materials and Methods and Results sections of the original article on pancreatic dimensions and adipose tissue. Key corrections include updated categorizations of daily activity durations and clarification of statistical results related to pancreatic fat fraction (PFF) and pancreatic volume index (PVI).

Background

The original study investigated factors influencing pancreatic size and adipose tissue in a large UK cohort, focusing on ethnicity, genetics, and associated health risks. Accurate measurement and categorization of lifestyle variables such as physical activity, screen time, and sleep duration are critical for interpreting associations with pancreatic metrics. The study also examined differences in pancreatic fat and volume across ethnic groups and diabetes status.

Data Highlights

Corrections include changing time spent watching television and computer use from weekly to daily thresholds (≤4 hours/day vs >4 hours/day). Additionally, a statistical result was corrected to indicate that pancreatic fat fraction (PFF), not pancreatic volume index (PVI), is significantly higher in White participants compared to Asian or Black participants. Another correction clarified that participants with diabetes, not without, showed no relationship between PVI and sleep duration.

Key Findings

• Time spent watching television and using computers was recategorized from weekly to daily thresholds for analysis.
• Pancreatic fat fraction (PFF), rather than pancreatic volume index (PVI), is significantly higher in White participants compared to Asian and Black participants after adjusting for age and sex.
• The relationship between pancreatic volume index and sleep duration was clarified to pertain to participants with diabetes, not those without diabetes.
• The corrections ensure accurate interpretation of associations between lifestyle factors, ethnicity, and pancreatic measurements.

Clinical Implications

These corrections refine the understanding of how lifestyle factors and ethnicity relate to pancreatic adiposity and volume. Clinicians and researchers should consider daily rather than weekly screen time thresholds when assessing risk factors. Accurate differentiation between pancreatic fat and volume metrics is essential for evaluating metabolic risk across ethnic groups and diabetes status.

Conclusion

The published corrections improve the accuracy of the original study's methodology and results, thereby enhancing the reliability of conclusions regarding pancreatic dimensions, adiposity, and their associations with lifestyle and ethnicity in the UK Biobank cohort.

References

1. Kongara et al. 2025 -- Factors Influencing Pancreatic Dimensions and Adipose Tissue in the UK Biobank: The Role of Ethnicity, Genetic Factors, and Associated Risks (Correction)