Clinical Report: Real-World Assessment of Prescription Glucosamine Sulfate
Overview
This study evaluates the effectiveness and tolerability of prescription glucosamine sulfate (pGS) in Filipino patients with knee osteoarthritis (KOA). Results indicate significant improvements in pain, stiffness, and function over an 8-week period.
Background
Knee osteoarthritis (KOA) is a prevalent condition that significantly impacts the quality of life, especially among older adults. With no known cure and limited disease-modifying interventions available, effective symptomatic treatments are essential. Prescription glucosamine sulfate has been studied for managing KOA symptoms.
Data Highlights
Outcome
Baseline
Week 8
LS Mean Change
WOMAC Pain
-
-
-11.96 (95% CI: -12.26 to -11.67)
VAS Pain
68.4 mm
11.9 mm
-
Patient Satisfaction
-
-
98.78%
Key Findings
281 Filipino adults with mild-to-moderate KOA were enrolled in the study.
98.6% of participants completed the study, with 88% receiving pGS monotherapy.
47% of patients achieved ≥50% pain reduction by Week 4.
Adverse events occurred in 4.6% of patients, mostly mild, with only one withdrawal.
Patients with more advanced KOA also showed significant pain improvement with pGS.
Clinical Implications
The findings indicate that prescription glucosamine sulfate was associated with improvements in symptoms of knee osteoarthritis in Filipino patients.
Conclusion
Prescription glucosamine sulfate improved pain, stiffness, and function in Filipino patients with knee osteoarthritis over the study period.
