High-intensity interval training after stroke: a three-level random-effects meta-analysis with cluster-robust inference and exploratory dose-parameter signals - Report - MDSpire
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High-intensity interval training after stroke: a three-level random-effects meta-analysis with cluster-robust inference and exploratory dose-parameter signals
Clinical Report: Effects of High-Intensity Interval Training on Post-Stroke Outcomes
Overview
This meta-analysis evaluates the effects of high-intensity interval training (HIIT) on balance, walking outcomes, and physiological endpoints in post-stroke populations.
Background
Stroke is a leading cause of long-term disability, often resulting in persistent impairments in balance and mobility. Effective rehabilitation strategies are crucial for improving functional outcomes and quality of life in stroke survivors. High-intensity interval training (HIIT) has emerged as a potential intervention to enhance recovery.
Data Highlights
Outcome
Effect Size (ES)
95% Confidence Interval (CI)
p-value
Balance (Berg Balance Scale)
0.20
0.01 to 0.39
0.039
Walking Endurance (6-min walk test)
0.41
0.22 to 0.61
<0.001
10-meter walk test time
0.06
−0.16 to 0.29
0.579
Cardiorespiratory Fitness
0.36
0.05 to 0.66
0.021
Systolic Blood Pressure
0.05
−0.25 to 0.36
0.722
Diastolic Blood Pressure
0.25
−0.05 to 0.56
0.099
Stroke Severity (Scandinavian Stroke Scale)
0.29
−0.04 to 0.62
0.084
Key Findings
HIIT may improve balance post-stroke (ES = 0.20, low certainty).
HIIT may enhance walking endurance (ES = 0.41, very low certainty).
No significant effect on short-distance walking speed (10-meter walk test, ES = 0.06).
Possible improvement in cardiorespiratory fitness (ES = 0.36, very low certainty).
Effects on blood pressure and stroke severity remain uncertain.
Exploratory analyses indicate variability in outcomes related to training-load parameters.
Clinical Implications
Clinicians should consider the outcomes of HIIT when designing rehabilitation programs.
Conclusion
In summary, low- to very-low-certainty evidence indicates that HIIT may impact balance, walking endurance, and cardiorespiratory fitness after stroke.
