Most common, burdensome, and worrisome symptoms experienced by people living with early Parkinson’s disease in Germany and the United States—Results from a cross-sectional survey - Report - MDSpire
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Most common, burdensome, and worrisome symptoms experienced by people living with early Parkinson’s disease in Germany and the United States—Results from a cross-sectional survey
Clinical Report: Prevalent and Distressing Symptoms in Early Parkinson’s Disease
Overview
This study identifies the most common and burdensome symptoms experienced by individuals with early-stage Parkinson's disease (ePD) in the United States and Germany, with tremor reported by all participants and mobility issues and pain noted as significant symptoms, particularly in those diagnosed for 4-5 years.
Background
Parkinson's disease (PD) is a progressive neurodegenerative disorder affecting millions globally. While much research has focused on late-stage symptoms, this study aims to identify the symptom burden in early-stage PD to improve patient care.
Data Highlights
Symptom
Reported Frequency
Tremor
100%
Mobility Issues
Reported as burdensome
Pain
Reported as burdensome
Bradykinesia
30% higher in 4-5 year group
Memory Loss
30% higher in 4-5 year group
Cognitive Impairment
30% higher in 4-5 year group
Key Findings
All participants reported experiencing tremor.
Mobility issues and pain were frequently reported as burdensome symptoms.
Bradykinesia, memory loss, and cognitive impairment were reported more frequently in those diagnosed for 4-5 years.
Clinical Implications
The findings highlight the significant burden of both motor and non-motor symptoms in early-stage PD.
Conclusion
The study emphasizes the importance of evaluating symptom frequency and impact in early-stage PD.
