A clinical investigation using reflectance confocal microscopy to evaluate the add-on efficacy of the Shumin treatment instrument combined with doxycycline for rosacea - Report - MDSpire

A clinical investigation using reflectance confocal microscopy to evaluate the add-on efficacy of the Shumin treatment instrument combined with doxycycline for rosacea

  • By

  • Yimin He

  • Jing Yuan

  • Mengting Hu

  • Hui Wan

  • Ying Gao

  • May 25, 2026

  • 0 min

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Clinical Report: Evaluation of Shumin Device and Doxycycline in Rosacea

Overview

This study evaluates the effectiveness and safety of combining the Shumin treatment device with doxycycline versus doxycycline with red light therapy in treating rosacea. Results indicate a higher efficacy rate and improved quality of life in the experimental group using the Shumin device.

Background

Rosacea is a chronic inflammatory skin condition that significantly impacts patients' quality of life and is often challenging to treat. The study addresses the need for effective treatment strategies by comparing two adjunctive therapies to oral doxycycline. Understanding the efficacy of these combined treatments can help optimize management for patients suffering from rosacea.

Data Highlights

GroupEfficacy RateDermatology Life Quality Index ImprovementDemodex Count ReductionRelapse Rate
Shumin Device + Doxycycline93.3%Superior ImprovementNo Significant DifferenceLower (p = 0.026)
Red Light Therapy + Doxycycline80.0%ImprovementNo Significant DifferenceHigher

Key Findings

  • The experimental group (Shumin device) had a 93.3% efficacy rate compared to 80.0% in the control group (red light therapy).
  • Both groups showed significant reductions in Dermatology Life Quality Index scores (p < 0.001).
  • Improvements in affected hair follicle counts were significantly better in the experimental group (p < 0.05).
  • No significant difference in total Demodex count reduction was observed between the groups.
  • The relapse rate was significantly lower in the experimental group (p = 0.026).

Clinical Implications

The findings suggest that the Shumin treatment device may offer superior clinical outcomes when used alongside doxycycline for rosacea management. Clinicians may consider this combination as a viable option for improving patient quality of life and reducing relapse rates.

Conclusion

The Shumin device, when used in conjunction with doxycycline, demonstrates improved efficacy and safety compared to red light therapy for treating rosacea. These results support further exploration of combined treatment strategies.

Related Resources & Content

  1. Ophthalmology Management, 2018 -- Relieving severe rosacea with IPL
  2. Conexiant -- AOPT Plus Collagen May Ease Rosacea
  3. Optometric Management, 2026 -- Recognizing and Treating Ocular Rosacea in Darker Skin Tones
  4. National Rosacea Society, 2025 -- Updated Rosacea Treatment Algorithms
  5. JAMA Dermatology, 2025 -- Efficacy, Safety, and Tolerability of Oral DFD-29
  6. PubMed -- Laser and energy-based devices for treating rosacea
  7. Optometric Management — Recognizing and Treating Ocular Rosacea in Darker Skin Tones
  8. National Rosacea Society Introduces Updated Rosacea Treatment Algorithms | Rosacea.org
  9. Efficacy, Safety, and Tolerability of Oral DFD-29, a Low-Dose Formulation of Minocycline, in Rosacea: Two Phase 3 Randomized Clinical Trials | Trials | JAMA Dermatology | JAMA Network
  10. Laser and energy-based devices for treating rosacea - a systematic review and network meta-analysis - PubMed

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