Traditional Chinese medicine–based modulation of gut microbiota in coronary heart disease: probiotic synergy and translational perspectives - Report - MDSpire
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Traditional Chinese medicine–based modulation of gut microbiota in coronary heart disease: probiotic synergy and translational perspectives
Clinical Report: Modulating Gut Microbiota in Coronary Heart Disease Through TCM
Overview
This review highlights the role of gut microbiota in coronary heart disease (CHD) and explores how Traditional Chinese Medicine (TCM) and probiotics may modulate microbial interactions.
Background
Coronary heart disease (CHD) is a leading cause of mortality globally, with its incidence rising due to lifestyle factors and metabolic syndrome. Gut microbiota has been implicated in CHD pathogenesis through mechanisms involving microbial metabolites that influence inflammation and vascular health.
Data Highlights
No specific numerical data or trial data presented in the article.
Key Findings
['Gut microbiota contributes to the pathogenesis of CHD through metabolites like TMAO and SCFAs.', 'Phytomedicine can modulate microbial metabolism and enhance intestinal barrier function.', 'Probiotics may provide targeted support to complement phytomedicine in restoring microbial balance.', 'Current challenges include the lack of standardization in phytomedicine-probiotic combinations and limited clinical evidence.', 'Microbiota characteristics in CHD patients include reduced SCFA production and increased TMAO-producing bacteria.']
Clinical Implications
Clinicians should consider the potential of phytomedicine and probiotics while being aware of the current limitations in evidence and standardization.
Conclusion
Further investigation is warranted to establish the efficacy and safety of phytomedicine and probiotics in addressing gut dysbiosis in CHD.
