Right atrial appendage thrombosis after percutaneous left atrial appendage occlusion: a case report - Report - MDSpire

Right atrial appendage thrombosis after percutaneous left atrial appendage occlusion: a case report

  • By

  • Haohui Du

  • Lijun Zeng

  • Xiaobo Pu

  • June 17, 2026

  • 0 min

Share

Thrombosis of the Right Atrial Appendage Following LAAO: A Case Study

Overview

This case report details the development of right atrial appendage (RAA) thrombosis in a 72-year-old man with atrial fibrillation after percutaneous left atrial appendage occlusion (LAAO). The patient was successfully treated with rivaroxaban, highlighting the need for vigilance regarding thrombus formation in the right atrium post-LAAO.

Background

Left atrial appendage occlusion (LAAO) is a recognized method for stroke prevention in patients with atrial fibrillation (AF) who cannot use long-term anticoagulation. While LAAO effectively reduces the risk of left-sided thromboembolic events, it does not eliminate the risk of thrombus formation in other cardiac chambers, particularly the right atrial appendage (RAA). Understanding the potential for RAA thrombosis is crucial for managing patients post-LAAO, especially those with additional risk factors.

Data Highlights

No numerical data or trial data presented in the article.

Key Findings

  • RAA thrombosis can occur in patients with AF following LAAO, particularly in those with heart failure and enlarged cardiac chambers.
  • The patient in this case study developed RAA thrombosis one year after LAAO with an Amplatzer Cardiac Plug.
  • Transthoracic echocardiography and cardiac CT confirmed the presence of a mobile thrombus in the RAA.
  • Anticoagulation with rivaroxaban led to the complete resolution of the thrombus within two weeks.
  • Clinicians should monitor for right-sided intracardiac thrombi in patients post-LAAO, even after successful procedures.

Clinical Implications

Healthcare professionals should remain alert to the risk of RAA thrombosis in patients with AF who have undergone LAAO, particularly those with heart failure. The decision to discontinue anticoagulation after LAAO must be individualized based on the patient's risk factors and clinical status.

Conclusion

This case underscores the importance of ongoing monitoring for thrombus formation in the right atrium following LAAO. Vigilance in anticoagulation management is essential to mitigate the risk of thromboembolic events.

Related Resources & Content

  1. Frontiers in Cardiovascular Medicine, 2026 -- The impact of preoperative left atrial appendage thrombus on surgical outcomes in atrial fibrillation patients undergoing epicardial left atrial appendage closure
  2. Pediatric Cardiology, 2011 -- Transcatheter Closure of Congenital Right Atrial Fistula Using the Amplatzer Occluder: A Case Report
  3. Pediatric Cardiology, 2011 -- Ischemic Stroke Resulting from Paradoxical Embolism Following a Failed Transcatheter Atrial Septal Defect Closure: A Cautionary Note
  4. Frontiers in Cardiovascular Medicine, 2026 -- Comparative Study on the Efficacy and Safety of Different Left Atrial Appendage Occluders in One-Stop Atrial Fibrillation Procedures
  5. 2023 ACC/AHA/ACCP/HRS Guideline for the Diagnosis and Management of Atrial Fibrillation: A Report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines | JACC
  6. 5-Year Results From the AMPLATZER Amulet Left Atrial Appendage Occluder Randomized Controlled Trial | JACC
  7. Frontiers, 2026 -- Right Atrial Appendage Thrombosis After Percutaneous Left Atrial Appendage Occlusion: A Case Report
  8. 2023 ACC/AHA/ACCP/HRS Guideline for the Diagnosis and Management of Atrial Fibrillation: A Report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines | JACC
  9. 5-Year Results From the AMPLATZER Amulet Left Atrial Appendage Occluder Randomized Controlled Trial | JACC
  10. Frontiers | Right Atrial Appendage Thrombosis After Percutaneous Left Atrial Appendage Occlusion: A Case Report

Original Source(s)

Related Content