Creation and assessment of a software tool for histoanatomical morphometric evaluation of the intestinal wall in pediatric patients with Hirschsprung’s disease - Report - MDSpire

Creation and assessment of a software tool for histoanatomical morphometric evaluation of the intestinal wall in pediatric patients with Hirschsprung’s disease

  • By

  • Tebin Hawez

  • Tobias Erlöv

  • Christina Granéli

  • Gustav Andersson

  • Tyra Lundberg

  • Emma Fransson

  • Maria Evertsson

  • Magnus Cinthio

  • Pernilla Stenström

  • March 21, 2026

  • 0 min

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Clinical Report: Software Tool for Histoanatomical Evaluation in Hirschsprung’s Disease

Overview

{'add': 'specific features of the program that enhance measurement efficiency.'}

Background

{'add': 'details on the limitations of traditional methods.'}

Data Highlights

{'remove': 'placeholder text.'}

Key Findings

{'rephrase': 'to ensure clarity and support from source material.'}

Clinical Implications

{'expand': 'on the impact of reduced variability on clinical outcomes.'}

Conclusion

{'add': 'significance of the software tool in current clinical practices.'}

References

  1. ERNICA guidelines for the management of rectosigmoid Hirschsprung’s disease - PMC, 2020 -- ERNICA guidelines
  2. The Diagnostic Value of Immunohistochemistry Markers in Hirschsprung Disease; A Systematic Review and Meta-analysis - ScienceDirect, 2024 -- Diagnostic Value of Immunohistochemistry
  3. Total Transanal Endorectal Pull-through Versus Laparoscopic-Assisted Approach in Children with Rectosigmoid Hirschsprung's Disease: A Systematic Review and Meta-Analysis - PubMed, 2023 -- Systematic Review on Surgical Approaches
  4. Journal of Crohn's and Colitis — Artificial intelligence-assisted approach to assessing bowel wall thickness in pediatric inflammatory bowel disease using intestinal ultrasound images
  5. European Radiology — Evaluation of Volumetric versus Linear Assessment of Intestinal Inflammation and Therapeutic Outcomes in Pediatric Patients with Newly Diagnosed Ileal Crohn Disease
  6. Journal of Crohn's and Colitis — Development of an Automated Tool for the Estimation of Histological Remission in Ulcerative Colitis Using Single-Wavelength Endoscopy Technology
  7. European Radiology — Automated Volumetric Segmentation of the Bowel in Body CT Scans Using Deep Learning Techniques
  8. ERNICA guidelines for the management of rectosigmoid Hirschsprung’s disease - PMC
  9. The Diagnostic Value of Immunohistochemistry Markers in Hirschsprung Disease; A Systematic Review and Meta-analysis - ScienceDirect
  10. Total Transanal Endorectal Pull-through Versus Laparoscopic-Assisted Approach in Children with Rectosigmoid Hirschsprung's Disease: A Systematic Review and Meta-Analysis - PubMed

Original Source(s)

Creation and assessment of a software tool for histoanatomical morphometric evaluation of the intestinal wall in pediatric patients with Hirschsprung’s disease

  • by Tebin Hawez, Tobias Erlöv, Christina Granéli, Gustav Andersson, Tyra Lundberg, Emma Fransson, Maria Evertsson, Magnus Cinthio, Pernilla Stenström

  • March 21, 2026

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