Determinants of Astigmatism in Grafts Following Corneal Transplantation for Keratoconus - Report - MDSpire

Determinants of Astigmatism in Grafts Following Corneal Transplantation for Keratoconus

  • By

  • Sepehr Feizi

  • Mohammad Ali Javadi

  • Sina Khosravi Mirzaei

  • Firouze Hatami

  • Kia Bayat

  • Mohammad Abolhosseini

  • Hamed Esfandiari

  • Zahra Khorrami

  • February 6, 2026

  • 0 min

Share

Determinants of Astigmatism in Grafts Following Corneal Transplantation for Keratoconus

Overview

This study evaluates the multifactorial determinants of astigmatism in grafts following corneal transplantation for keratoconus. It highlights the influence of various preoperative, intraoperative, and postoperative variables on graft astigmatism in a large cohort of patients.

Background

Corneal transplantation for keratoconus often results in excellent graft survival but can be complicated by post-keratoplasty astigmatism, which may limit visual acuity. Understanding the factors contributing to this astigmatism is crucial for improving patient outcomes and guiding surgical techniques. Previous studies have identified several risk factors, but a comprehensive evaluation of multiple variables in a large cohort has been lacking.

Data Highlights

No numerical data available in the source material.

Key Findings

  • Post-keratoplasty astigmatism is a common complication that can significantly affect visual rehabilitation.
  • Factors influencing graft astigmatism include graft size, donor-recipient size discrepancy, and timing of suture removal.
  • The etiology of astigmatism is multifactorial, involving recipient-related, donor-related, and surgical factors.
  • Modern keratoplasty techniques have evolved, focusing on targeted procedures to minimize complications.
  • Stepwise, data-guided suture management may help control astigmatism in keratoconus grafts.

Clinical Implications

Surgeons should consider a broad range of factors when planning corneal transplantation for keratoconus to minimize post-operative astigmatism. A tailored approach to suture management and careful selection of surgical techniques can enhance visual outcomes for patients.

Conclusion

This study underscores the complexity of post-keratoplasty astigmatism and the need for comprehensive preoperative planning. Addressing the identified determinants can improve visual rehabilitation after corneal transplantation.

References

  1. Various Authors, Source, Year -- Determinants of Astigmatism in Grafts Following Corneal Transplantation for Keratoconus
  2. Contact Lens Spectrum — SPARE THE CAUTION, SPOIL THE GRAFT
  3. Contact Lens Spectrum — Contact Lens Case Reports
  4. Optometric Management — CONTACT LENSES: KCN: Post-graft fitting Recommendations
  5. Ophthalmology Management — Reducing Post-PK Astigmatism
  6. SPARE THE CAUTION, SPOIL THE GRAFT
  7. Contact Lens Case Reports
  8. CONTACT LENSES: KCN: Post-graft fitting Recommendations
  9. Reducing Post-PK Astigmatism
  10. Factors associated with graft astigmatism after corneal transplantation for keratoconus
  11. The Second Global Consensus on Keratoconus
  12. Effect of selective suture removal on graft astigmatism after corneal transplantation in keratoconus

Original Source(s)

Related Content