Clinical Report: Migraine: Acute, Preventive and Interventional Strategies

Background

Migraine is a prevalent condition in pediatric populations. A multidisciplinary approach that combines pharmacologic and non-pharmacologic therapies is essential for care.

Data Highlights

No numerical data available in the source material.

Key Findings

• Acute treatment strategies include triptans, gepants, and non-specific analgesics.
• Preventive pharmacological options encompass oral medications and CGRP monoclonal antibodies.
• Interventional procedures such as botulinum toxin injections and nerve blocks are recognized for migraine management.
• Non-pharmacological approaches include neuromodulation devices and lifestyle modifications.
• Fremanezumab has been shown to reduce monthly migraine days in pediatric patients.

Clinical Implications

Healthcare professionals should consider a combination of therapies tailored to individual patient needs for migraine management.

Conclusion

A comprehensive approach to migraine management in pediatric patients is essential.

Related Resources & Content

1. AAN/AHS, Neurology, 2019 -- Practice guideline update summary: Acute treatment of migraine in children and adolescents
2. Fremanezumab in Children and Adolescents with Episodic Migraine, NEJM, 2025 -- Fremanezumab in Children and Adolescents with Episodic Migraine
3. conexiant — IHS, ACP Differ on Migraine Tx
4. Drugs - Real World Outcomes — Factors Influencing the Limited Effectiveness of Acute Migraine Treatments in Japan: Findings from the OVERCOME (Japan) Observational Study on Migraine Epidemiology, Treatment, and Care
5. optometric management — Glaucoma: Embracing Interventional Management
6. Frontiers in Neurology — Premenstrual syndrome, premenstrual dysphoric disorder, and coping strategies in women with menstrual migraine
7. IHS, ACP Differ on Migraine Tx
8. Factors Influencing the Limited Effectiveness of Acute Migraine Treatments in Japan
9. Practice guideline update summary: Acute treatment of migraine in children and adolescents | Neurology
10. Fremanezumab in Children and Adolescents with Episodic Migraine | New England Journal of Medicine
11. Greater occipital nerve block for chronic headache management in children and adolescents: A longitudinal observational study and systematic review - Morozova - 2025 - Headache: The Journal of Head and Face Pain - Wiley Online Library