Case Report: Pancreatic toxoplasmosis: role of endoscopic ultrasound in diagnosis - Report - MDSpire

Case Report: Pancreatic toxoplasmosis: role of endoscopic ultrasound in diagnosis

  • By

  • Cosmas Rinaldi A. Lesmana

  • Randy Adiwinata

  • Jennifer Simca

  • Caroline Tanadi

  • Kevin Tandarto

  • Stella Marleen

  • Daniel Ruslim

  • Joyce Bratanata

  • June 4, 2026

  • 0 min

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Clinical Report: The Impact of Endoscopic Ultrasound on Diagnosing Pancreatic Toxoplasmosis

Overview

This case study presents a rare instance of pancreatic toxoplasmosis diagnosed via endoscopic ultrasound (EUS) in a 48-year-old male patient.

Background

Toxoplasmosis is a zoonotic infection caused by Toxoplasma gondii, often presenting as encephalitis in immunocompromised patients. Extracerebral manifestations, such as pancreatic involvement, are rare.

Data Highlights

No numerical data or trial data available in the article.

Key Findings

  • A 48-year-old male presented with pancreatic nodules and neurological symptoms.
  • Initial imaging suggested a primary pancreatic malignancy due to hypermetabolic activity.
  • Endoscopic ultrasound revealed multiple hypoechoic nodules in the pancreas.
  • EUS-guided fine needle biopsy confirmed chronic inflammation without malignancy.
  • Histopathological examination identified T. gondii organisms, establishing the diagnosis of pancreatic toxoplasmosis.

Clinical Implications

Clinicians should consider infectious etiologies in the differential diagnosis of pancreatic masses.

Conclusion

The diagnosis of pancreatic toxoplasmosis can be established through EUS-guided biopsy.

Related Resources & Content

  1. CDC, Clinical Care of Toxoplasmosis | Toxoplasmosis, 2026 -- Clinical Care of Toxoplasmosis
  2. Journal of Gastroenterology, Role of Endoscopic Ultrasonography in the Diagnosis of Pancreatic Cancer, 2018 -- Role of Endoscopic Ultrasonography in the Diagnosis of Pancreatic Cancer
  3. Surgical Endoscopy, Assessing the Role of Endoscopic Ultrasonography in Differentiating Between Benign and Malignant Intraductal Papillary Mucinous Neoplasms, 2022 -- Assessing the Role of Endoscopic Ultrasonography in Differentiating Between Benign and Malignant Intraductal Papillary Mucinous Neoplasms
  4. Open Forum Infectious Diseases, Evaluating the Role and Challenges of Polymerase Chain Reaction (PCR) in Diagnosing and Managing Toxoplasmosis After Allogeneic Hematopoietic Cell Transplant, 2022 -- Evaluating the Role and Challenges of Polymerase Chain Reaction (PCR) in Diagnosing and Managing Toxoplasmosis After Allogeneic Hematopoietic Cell Transplant
  5. Surgical Endoscopy — Comparative Analysis of Contrast-Enhanced Endoscopic Ultrasound-Guided Fine Needle Biopsy Versus Standard Fine Needle Biopsy: A Retrospective Investigation at a Medical Facility
  6. Clinical Care of Toxoplasmosis | Toxoplasmosis | CDC
  7. Comparative diagnostic performance of endoscopic ultrasound, MRI, and CT for preoperative assessment of pancreatic cancer: a Bayesian network meta-analysis under a graded reference standard | BMC Medical Imaging | Springer Nature Link

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