Predictive value of water swallow test score, serum albumin, and systemic immune-inflammation index for stroke-associated pneumonia in patients with acute isolated pontine infarction - Report - MDSpire

Predictive value of water swallow test score, serum albumin, and systemic immune-inflammation index for stroke-associated pneumonia in patients with acute isolated pontine infarction

  • By

  • Jingjing Ding

  • Haifeng Jin

  • Xiaomei Ren

  • Jieli Geng

  • July 14, 2026

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Clinical Report: Predictors of Stroke-Associated Pneumonia in AIPI Patients

Overview

This study identifies independent predictors of stroke-associated pneumonia (SAP) in patients with acute isolated pontine infarction (AIPI) and assesses the association between SAP and short-term prognosis. Key predictors include Water Swallow Test scores, serum albumin levels, and the systemic immune-inflammation index.

Background

Stroke-associated pneumonia (SAP) is a significant complication following acute ischemic stroke, leading to increased disability and mortality. Acute isolated pontine infarction (AIPI) is particularly associated with a high risk of SAP due to factors such as dysphagia. Identifying predictors specific to AIPI can enhance early risk stratification and preventive strategies.

Data Highlights

VariableValue
SAP Incidence10.61%
WST Score OR2.622
Serum Albumin OR0.831
SII OR1.004
AUC0.938
Sensitivity89.5%
Specificity86.9%

Key Findings

  • SAP occurred in 10.61% of patients with AIPI.
  • Patients with SAP were older and had higher WST scores and NIHSS scores.
  • Independent predictors of SAP included WST score, serum albumin level, and SII.
  • The combined model of predictors demonstrated excellent predictive performance (AUC = 0.938).
  • SAP was associated with a significantly increased risk of poor functional outcomes (mRS score ≥ 3).

Clinical Implications

The identification of WST scores, serum albumin levels, and SII as predictors of SAP can aid clinicians in early identification of at-risk patients. Implementing these predictors in clinical practice may facilitate timely interventions to prevent SAP in patients with AIPI.

Conclusion

The study highlights the importance of specific predictors for SAP in AIPI patients, which can inform clinical decision-making and improve patient outcomes.

Related Resources & Content

  1. Author(s)/Org, Source, Year -- Title
  2. Author(s)/Org, Source, Year -- Title
  3. Author(s)/Org, Source, Year -- Title
  4. European stroke organisation guideline on stroke-associated pneumonia - PMC
  5. 2026 Guideline for the Early Management of Patients With Acute Ischemic Stroke: A Guideline From the American Heart Association/American Stroke Association
  6. Frontiers in Psychiatry — The association between systemic immune-inflammation index and post-stroke depression: a meta-analysis
  7. Prevalence, risk factors, and outcomes of dysphagia after stroke: a systematic review and meta-analysis
  8. Role of serum albumin levels in stroke-associated pneumonia: A systematic review and meta-analysis
  9. Elevated systemic immune-inflammation index is associated with stroke-associated pneumonia in acute ischemic stroke: a retrospective cohort study
  10. European stroke organisation guideline on stroke-associated pneumonia - PMC
  11. 2026 Guideline for the Early Management of Patients With Acute Ischemic Stroke: A Guideline From the American Heart Association/American Stroke Association
  12. ABSTRACT NUMBER: ESOC2026A74 PREDICTORS, SCREENING TOOLS, AND PROGNOSTIC MODELS FOR STROKE-ASSOCIATED ASPIRATION PNEUMONIA: A PRISMA-SCR–GUIDED SCOPING REVIEW WITH IMPLICATIONS FOR LOW-RESOURCE SETTINGS | European Stroke Journal | Oxford Academic

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