Brief report: joint trajectories of anxiety and depression symptoms in an inception cohort of autistic youth - Report - MDSpire

Brief report: joint trajectories of anxiety and depression symptoms in an inception cohort of autistic youth

  • By

  • Michelle C. Hunsche

  • Anat Zaidman-Zait

  • Melissa Olana

  • Peter Szatmari

  • Teresa Bennett

  • Eric Duku

  • Stelios Georgiades

  • Isabel M. Smith

  • Lonnie Zwaigenbaum

  • Mayada Elsabbagh

  • Tracy Vaillancourt

  • Rachael Bedford

  • Connor M. Kerns

  • May 5, 2026

  • 0 min

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Clinical Report: Concurrent Development of Anxiety and Depression in Autistic Youth

Overview

Revise to emphasize the significance of concurrent monitoring and its implications for early intervention.

Background

Anxiety and depression are prevalent among autistic youth, with rates significantly higher than their non-autistic peers. Understanding the progression of these symptoms during adolescence, a critical developmental period, is essential for effective identification and treatment. This study addresses a gap in the literature regarding the co-occurrence and interaction of anxiety and depression symptoms in autistic adolescents.

Data Highlights

No numerical data provided in the article.

Key Findings

  • Anxiety symptoms remained stable from childhood into adolescence, while depression symptoms increased on average.
  • There was significant heterogeneity in individual trajectories of anxiety and depression symptoms.
  • Greater autistic traits and emotional reactivity correlated with higher initial anxiety and depression symptoms.
  • Stronger communication ability was associated with more initial anxiety but a decrease in anxiety symptoms over time.
  • Joint monitoring of anxiety and depression symptoms is crucial for early detection and intervention.

Clinical Implications

Clinicians should prioritize the concurrent assessment of anxiety and depression symptoms in autistic adolescents, especially during the transition to adolescence. Understanding individual trajectories can inform tailored interventions and support strategies.

Conclusion

The findings underscore the need for integrated approaches to monitor and address anxiety and depression in autistic youth, particularly as they navigate the challenges of adolescence.

References

  1. BMC Psychiatry (Springer), 2023 -- The impact of the COVID-19 pandemic on the well-being of autistic and non-autistic adults in Eastern Germany
  2. Frontiers in Psychiatry, 2026 -- Barriers to Autonomy: Investigating the Impact of Self-Determination and Anxiety on Daily Living Abilities in Autistic Youth Transitioning to Adulthood
  3. BMC Psychiatry (Springer), 2023 -- The influence of psychosocial stress on functional connectivity and neuroendocrine markers in adolescents with depressive and comorbid anxiety disorders: a study protocol
  4. Frontiers in Psychiatry, 2026 -- Caregiver-reported sleep problems and suicidality in autistic youth: findings from a sleep diary study
  5. Emotion regulation in autistic adolescents: a mixed methods systematic review | Journal of Neurodevelopmental Disorders | Springer Nature Link
  6. Anxiety Disorders Resource Center
  7. Emotion regulation in autistic adolescents: a mixed methods systematic review | Journal of Neurodevelopmental Disorders | Springer Nature Link
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