Case Study: Unstable Late Migration of a Ventricular Septal Defect Closure Device with Endothelialization - Report - MDSpire

Case Study: Unstable Late Migration of a Ventricular Septal Defect Closure Device with Endothelialization

  • By

  • Min-Jung Jan

  • Chung-Chi Wang

  • Sheng-Ling Jan

  • Wei-Li Liu

  • April 20, 2026

  • 0 min

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Clinical Report: Unstable Late Migration of a VSD Closure Device

Overview

This case study presents an unusual instance of late migration of a ventricular septal defect (VSD) closure device, occurring 18 months post-implantation. The device exhibited complete circumferential endothelialization, indicating long-term tissue incorporation prior to its migration.

Background

Ventricular septal defects (VSDs) are the most common congenital heart defects, with transcatheter closure becoming a preferred treatment due to its minimally invasive nature. While device embolization typically occurs shortly after implantation, this case highlights the rare possibility of late migration, emphasizing the need for ongoing surveillance post-procedure.

Data Highlights

No numerical data or trial data presented in the article.

Key Findings

  • Late device migration after VSD closure is exceedingly rare, with this case occurring 18 months post-procedure.
  • The device demonstrated complete circumferential endothelialization, indicating successful long-term tissue incorporation.
  • Serial imaging showed stable device positioning prior to migration, suggesting no early malposition or technical error.
  • Transcatheter closure of perimembranous VSDs using the Konar-MFO device has shown high procedural success rates and low complication profiles.
  • Device embolization is typically associated with early post-procedural periods, with an estimated incidence of approximately 0.4%.

Clinical Implications

This case underscores the importance of long-term follow-up and imaging after transcatheter VSD closure to monitor for potential late complications. Clinicians should be aware of the rare possibility of late device migration despite initial successful implantation.

Conclusion

The occurrence of late device migration in this case highlights the need for vigilance in post-procedural monitoring of VSD closure devices. Continued research and reporting on such rare events are essential for improving patient outcomes.

References

  1. Pediatric Cardiology, Outcomes of Interventional Closure for Ventricular Septal Defects: Insights from a Single-Center Study in Pediatric and Adult Populations, 2020
  2. Pediatric Cardiology, Closure of Isolated Congenital Ventricular Septal Defects Using a Percutaneous Approach: A Retrospective Analysis of 412 Cases from a Single Institution, 2020
  3. Clinical Research in Cardiology, Outcomes of Long-Term Closure of Perimembranous Ventricular Septal Defects with the Nit-Occlud® Lê VSD Coil System, 2020
  4. 2018 AHA/ACC Guideline for the Management of Adults With Congenital Heart Disease (ACHD) Slide Set
  5. Pediatric Cardiology — Creation of Transcatheter Ventricular Septal Defects for Restrictive VSD in Cases of Double-Outlet Right Ventricle
  6. 2018 AHA/ACC Guideline for the Management of Adults With Congenital Heart Disease (ACHD) Slide Set
  7. Early and mid-term outcomes of transcatheter closure of perimembranous ventricular septal defects using double-disc occluders - PubMed
  8. Word of caution: silent late device embolisation after perimembranous ventricular septal defect closure in a 6-Kg infant - PubMed

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