Pneumonia Etiology and Risk Factors in a Tertiary Hospital During the COVID-19 Era: A Retrospective Analysis (2020–2024) - Report - MDSpire

Pneumonia Etiology and Risk Factors in a Tertiary Hospital During the COVID-19 Era: A Retrospective Analysis (2020–2024)

  • By

  • Nikolaus Clodi

  • Friedrich Berthold

  • Thomas Berger

  • Martin Clodi

  • Michael Resl

  • July 13, 2026

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Clinical Report: Analysis of Pneumonia Causes and Associated Risk Factors

Overview

This retrospective study examines pneumonia causes and risk factors during the COVID-19 pandemic in a tertiary care setting.

Background

Pneumonia remains a leading infectious cause of death globally, particularly affecting older adults and those with multiple comorbidities. The COVID-19 pandemic has complicated pneumonia diagnosis and treatment.

Data Highlights

No numerical data available in the provided source material.

Key Findings

  • Pneumonia diagnosis was established based on clinical signs and radiological evidence.
  • Pathogen identification remains challenging, with 40-60% of cases having undetected organisms.
  • Comorbidities such as chronic kidney disease and malignancy are associated with increased mortality.
  • The study population consisted predominantly of elderly, multimorbid, and male patients.
  • Body weight and HDL cholesterol levels were linked to survival outcomes.

Clinical Implications

Understanding the shifting etiological spectrum of pneumonia during the COVID-19 pandemic is crucial for improving diagnostic and treatment strategies. Clinicians should consider traditional and emerging risk factors when assessing pneumonia patients.

Conclusion

This study highlights the complexities of pneumonia management during the COVID-19 pandemic and the need for ongoing research into its causes and associated risk factors.

Related Resources & Content

  1. Infection, 2023 -- Significant Impact of RSV and Influenza on Patients with Suspected Pneumonia
  2. Intensive Care Medicine, 2022 -- Evaluation of Radiographic Pneumothorax and Pneumomediastinum in Acute Respiratory Distress Syndrome
  3. Open Forum Infectious Diseases, 2021 -- A Retrospective Study of Pneumocystis jirovecii Pneumonia
  4. Infection, 2024 -- Impact of the COVID-19 Pandemic on Clinical Features and Outcomes in Adults with Pneumococcal Meningitis
  5. Global burden of lower respiratory infections
  6. Clinical management of COVID-19: living guideline, June 2025
  7. IDSA/PIDS 2026 Guidelines for the Management of Community-Acquired Pneumonia
  8. https://academic.oup.com/ajrccm/article/212/1/24/8435770?login=false
  9. Interventions To Prevent Nonventilator Hospital-Acquired Pneumonia | Effective Health Care (EHC) Program

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