Editorial: Comprehensive management and risk assessment of breast cancer-related lymphedema: a multidisciplinary approach - Report - MDSpire

Editorial: Comprehensive management and risk assessment of breast cancer-related lymphedema: a multidisciplinary approach

  • By

  • Joseph M. Escandón

  • Chihiro Matsui

  • Pedro Ciudad

  • Oscar J. Manrique

  • June 4, 2026

  • 0 min

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Clinical Report: Holistic Strategies and Risk Evaluation for Lymphedema

Overview

This editorial discusses the increasing prevalence of breast cancer-related lymphedema (BCRL) and highlights the importance of multidisciplinary approaches for its management. It emphasizes the need for early risk identification and presents predictive models that can guide individualized postoperative care.

Background

Breast cancer-related lymphedema is a significant complication affecting survivors, leading to physical and psychosocial challenges. As breast cancer survival rates improve, the incidence of BCRL has risen, necessitating effective management strategies. Understanding the condition's pathophysiology and treatment options is crucial for enhancing patient quality of life.

Data Highlights

No specific numerical data or trial results were provided in the source material.

Key Findings

  • BCRL is a chronic condition that can severely impair quality of life due to physical and psychosocial effects.
  • Sentinel lymph node biopsy (SLNB) reduces the incidence of postoperative lymphedema compared to axillary lymph node dissection.
  • Emerging evidence suggests that omitting sentinel node procedures in selected patients may further lower BCRL risk.
  • Predictive models for seroma resolution and BCRL risk have been developed, showing strong performance in identifying high-risk patients.
  • Physical therapy modalities have been systematically reviewed, indicating their role in BCRL prevention and treatment.

Clinical Implications

Healthcare professionals should prioritize early risk assessment and implement multidisciplinary care pathways for patients at risk of BCRL. Utilizing predictive models can enhance individualized postoperative management and potentially improve patient outcomes.

Conclusion

The editorial underscores the importance of comprehensive management strategies for BCRL, highlighting the need for early identification and personalized care approaches.

Related Resources & Content

  1. ASCO Post, 2020 -- Reducing the Risk of Lymphedema in Patients With Cancer
  2. JAMA Network Open, 2020 -- Clinician Perspectives on Implementing Breast Cancer–Related Lymphedema Prospective Screening
  3. ASCO Post, 2019 -- Expert Point of View: Julie A. Margenthaler, MD Related Articles
  4. Frontiers in Oncology, 2026 -- Development and validation of a machine learning-based predictive model for early outcomes following combined suction-assisted lipectomy and lymphovenous anastomosis in breast cancer-related lymphedema
  5. International Society of Lymphology, 2023 -- The Diagnosis and Treatment of Peripheral Lymphedema: 2023 Consensus Document
  6. ACS, 2025 -- Omission of Axillary Surgery May Lower Risks of Patient Morbidity without Reducing Survival in Low-Risk Breast Cancers
  7. PubMed, 2023 -- Efficacy of Immediate Lymphatic Reconstruction in Prevention of Breast Cancer-Related Lymphedema: A Systematic Review and Meta-Analysis
  8. https://isl.arizona.edu/sites/default/files/2024-11/THE-DIAGNOSIS-AND-TREATMENT-OF-PERIPHERAL-LYMPHEDEMA-2023-CONSENSUS-DOCUMENT-OF-THE-INTERNATIONAL-SOCIETY-OF-LYMPHOLOGY.pdf
  9. Omission of Axillary Surgery May Lower Risks of Patient Morbidity without Reducing Survival in Low-Risk Breast Cancers | ACS
  10. Efficacy of Immediate Lymphatic Reconstruction in Prevention of Breast Cancer-Related Lymphedema: A Systematic Review and Meta-Analysis - PubMed

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